Maxillary sinus floor augmentation using a beta-tricalcium phosphate (Cerasorb) alone compared to autogenous bone grafts.
Maxillary sinus floor augmentation using a beta-tricalcium phosphate (Cerasorb) alone compared to autogenous bone grafts.
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发表时间：
2005-05
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通讯作者：
S. A. Zijderveld;I. R. Zerbo;J. V. D. van den Bergh;E. Schulten;C. T. ten Bruggenkate
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作者：
S. A. Zijderveld;I. R. Zerbo;J. V. D. van den Bergh;E. Schulten;C. T. ten Bruggenkate
目的：进行一项前瞻性人体临床研究，以确定2种移植材料，β-磷酸三钙（Cerasorb; Curasan，Kleinostheim，德国）和自体颏骨在上颌窦底提升手术中的临床和组织学骨形成能力。材料与方法10例健康患者在局部麻醉下接受双侧（n = 6）或单侧（n = 4）上颌窦底提升手术。在每种情况下，残留的上颌后部骨高度在4和8 mm之间。在双侧上颌窦底提升的情况下，原始骨用裂口设计增强，测试侧使用100% β-磷酸三钙，对侧对照侧使用100%颏骨。单侧病例使用100% β-磷酸三钙进行增强。在6个月的愈合期后，放置ITI全身螺钉型种植体（Straumann，Waldenburg，Switzerland）。在植入手术时，用3.5 mm环钻取出活检样本。结果共进行了16次窦底提升术。放置了41个种植体，26个在试验侧，15个在对照侧。植入时的临床特征不同，尤其是在临床外观和钻孔阻力方面。植入前通过X线片检查高度增加，发现在所有情况下均足够。经过平均近1年的随访，没有发生植入物丢失或失效。讨论本研究的临床结果很有希望，并且没有种植体失败，这可能主要是因为要求种植体位置的原始骨高度至少为4 mm。结论：尽管自体骨移植仍然是金标准，但根据临床结果，所使用的植入前窦底提升手术（涉及有限体积的β-磷酸三钙）似乎是该患者人群中临床可靠的手术。
PURPOSE A prospective human clinical study was conducted to determine the clinical and histologic bone formation ability of 2 graft materials, a beta-tricalcium phosphate (Cerasorb; Curasan, Kleinostheim, Germany) and autogenous chin bone, in maxillary sinus floor elevation surgery. MATERIALS AND METHODS Ten healthy patients underwent a bilateral (n = 6) or unilateral (n = 4) maxillary sinus floor elevation procedure under local anesthesia. In each case, residual posterior maxillary bone height was between 4 and 8 mm. In cases of bilateral sinus floor elevation, the original bone was augmented with a split-mouth design with 100% beta-tricalcium phosphate on the test side and 100% chin bone on the contralateral control side. The unilateral cases were augmented with 100% beta-tricalcium phosphate. After a healing period of 6 months, ITI full body screw-type implants (Straumann, Waldenburg, Switzerland) were placed. At the time of implant surgery, biopsy samples were removed with a 3.5-mm trephine drill. RESULTS Sixteen sinus floor elevations were performed. Forty-one implants were placed, 26 on the test side and 15 on the control side. The clinical characteristics at the time of implantation differed, especially regarding clinical appearance and drilling resistance. The increase in height was examined radiographically prior to implantation and was found to be sufficient in all cases. After a mean of nearly 1 year of follow-up, no implant losses or failures had occurred. DISCUSSION The promising clinical results of the present study and the lack of implant failures are probably mainly the result of requiring an original bone height of at least 4 mm at the implant location. CONCLUSION Although autogenous bone grafting is still the gold standard, according to the clinical results, the preimplantation sinus floor elevation procedure used, which involved a limited volume of beta-tricalcium phosphate, appeared to be a clinically reliable procedure in this patient population.