Dihydroisoquinoline copper(II) complexes: crystal structures, cytotoxicity, and action mechanism

Dihydroisoquinoline copper(II) complexes: crystal structures, cytotoxicity, and action mechanism
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二氢异喹啉铜(II)配合物:晶体结构、细胞毒性和作用机制

DOI:
10.1039/c5ra15789g
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发表时间:
2015-09
期刊:
影响因子:
3.9
通讯作者:
Hong Liang
Hong Liang
中科院分区:
化学3区
文献类型:
--
作者:
Ke-Bin Huang;Zhen-Feng Chen;Yan-Cheng Liu;Xiao-Li Xie;Hong Liang

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合成并表征了3种新的4,5-亚甲二氧基-1-吡啶二氢异喹啉(MPDQ)铜配合物[Cu 2(MPDQ)2Cl 4](1),[Cu(MPDQ)(H2O)(SO 4)](2)和[Cu 2(MPDQ)2(C2 O 4)(ClO 4)2](3)。它们表现出增强的细胞毒性,
Three new copper(II) complexes of 4,5-methylenedioxy-1-pyridinedihydroisoquinoline (MPDQ), [Cu2(MPDQ)2Cl4] (1), [Cu(MPDQ)(H2O)(SO4)] (2), and [Cu2(MPDQ)2(C2O4)(ClO4)2] (3) were synthesized and characterized. They exhibit enhanced cytotoxicity against the
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