Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach
Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach
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DOI：
10.1097/xeb.0000000000000055
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发表时间：
2015-09-01
影响因子：
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通讯作者：
Tungpunkom, Patraporn
中科院分区：
文献类型：
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作者：
Aromataris, Edoardo;Fernandez, Ritin;Tungpunkom, Patraporn
目的：随着可用系统性综述数量的增加，为医疗保健决策者提供他们所需证据的合理下一步是对现有系统性综述进行综述。现有系统性综述的综合有许多不同的名称，其中之一是伞式综述。总括审查允许对与审查问题相关的审查结果进行比较和对比。伞式综述的最大特点是，这种证据综合只考虑纳入最高级别的证据，即其他系统性综述和荟萃分析。乔安娜·布里格斯研究所成立了一个方法问题工作组，为开展总括审查制定方法指南，包括各种类型的定量和定性证据。本研究的目的是描述的发展和指导进行的伞式review.Methods：讨论和测试的方法进行伞式review的要素举行了6个月的时间内由一个方法工作组的成员。工作组由6名参与者组成，他们在开发期间通过电话会议、电子邮件和面对面会议进行通信。2013年10月，在乔安娜·布里格斯研究所会议的一个讲习班上介绍了这一方法。研讨会的参与者，审查的作者和方法学家提供了进一步的测试，批评和反馈的建议methodologist.Results：本研究描述了方法和方法的开展伞式审查，包括出版的系统评价和荟萃分析作为分析单元的审查。提供了关于总括审查基本要素的详细信息，包括以人群、干预措施、对照药物、结局格式、入选标准的细微差别和检索策略呈现审查问题。还开发和测试了一个关键评估工具，包括10个问题，以帮助评估系统综述和荟萃分析中的偏倚风险。相关的细节，以提取纳入审查和如何最好地呈现定量和定性的系统评价的结果，在一个读者友好的formatureoffered.Conclusions：伞审查提供了一个现成的手段，为决策者在医疗保健，以获得一个广泛的主题领域的清晰认识。本文所述的总括综述方法是第一个考虑报告来自随机对照试验的定量证据以外的综述。该方法包括一个易于使用和信息丰富的证据表摘要，随时为决策者提供与所提出的问题相关的可用的最高水平的证据。
Aims:With the increase in the number of systematic reviews available, a logical next step to provide decision makers in healthcare with the evidence they require has been the conduct of reviews of existing systematic reviews. Syntheses of existing systematic reviews are referred to by many different names, one of which is an umbrella review. An umbrella review allows the findings of reviews relevant to a review question to be compared and contrasted. An umbrella review's most characteristic feature is that this type of evidence synthesis only considers for inclusion the highest level of evidence, namely other systematic reviews and meta-analyses. A methodology working group was formed by the Joanna Briggs Institute to develop methodological guidance for the conduct of an umbrella review, including diverse types of evidence, both quantitative and qualitative. The aim of this study is to describe the development and guidance for the conduct of an umbrella review.Methods:Discussion and testing of the elements of methods for the conduct of an umbrella review were held over a 6-month period by members of a methodology working group. The working group comprised six participants who corresponded via teleconference, e-mail and face-to-face meeting during this development period. In October 2013, the methodology was presented in a workshop at the Joanna Briggs Institute Convention. Workshop participants, review authors and methodologists provided further testing, critique and feedback on the proposed methodology.Results:This study describes the methodology and methods developed for the conduct of an umbrella review that includes published systematic reviews and meta-analyses as the analytical unit of the review. Details are provided regarding the essential elements of an umbrella review, including presentation of the review question in a Population, Intervention, Comparator, Outcome format, nuances of the inclusion criteria and search strategy. A critical appraisal tool with 10 questions to help assess risk of bias in systematic reviews and meta-analyses was also developed and tested. Relevant details to extract from included reviews and how to best present the findings of both quantitative and qualitative systematic reviews in a reader friendly format are provided.Conclusions:Umbrella reviews provide a ready means for decision makers in healthcare to gain a clear understanding of a broad topic area. The umbrella review methodology described here is the first to consider reviews that report other than quantitative evidence derived from randomized controlled trials. The methodology includes an easy to use and informative summary of evidence table to readily provide decision makers with the available, highest level of evidence relevant to the question posed.