Mueggelone, a novel inhibitor of fish development from the fresh water cyanobacterium Aphanizomenon flos-aquae.
Mueggelone, a novel inhibitor of fish development from the fresh water cyanobacterium Aphanizomenon flos-aquae.
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Mueggelone 是一种新型鱼类发育抑制剂，来自淡水蓝藻束丝藻 (Aphanizomenon flos-aquae)。
DOI：
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发表时间：
1997
影响因子：
5.1
通讯作者：
A. Oberemm
中科院分区：
文献类型：
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作者：
O. Papendorf;G. König;A. Wright;I. Chorus;A. Oberemm
从野外采集的水华隐翅虫样品中分离得到一种新的C18脂类化合物，其中含有一个10元的内酯，乳胶酮(1)，以及已知的化合物羽扇豆烯基乙酸酯(3)。通过广泛的光谱分析(一维和二维核磁共振、MS、IR)确保了这两种结构的安全。生物活性评价表明，这两种化合物对鱼胚幼体发育均有明显的抑制作用。
A novel C18 lipid, containing a 10-membered lactone, mueggelone (1), was isolated from a field-collected sample of Aphanizomenon flos-aquae, together with the known compound lupenyl acetate (3). Both structures were secured using extensive spectroscopic analysis (1D and 2D NMR, MS, IR). Biological activity assessment of both compounds indicated them to have significant inhibitory effects on fish embryo larval development.