Chimeric receptors of the Arabidopsis thaliana pattern recognition receptors EFR and FLS2
Chimeric receptors of the Arabidopsis thaliana pattern recognition receptors EFR and FLS2
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DOI：
10.4161/psb.5.11.13312
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发表时间：
2010-01-01
影响因子：
2.9
通讯作者：
Felix, Georg
中科院分区：
文献类型：
--
作者：
Albert, Markus;Felix, Georg
FLS 2和EFR是拟南芥中感知细菌蛋白鞭毛蛋白和延伸因子Tu（EF-Tu）的模式识别受体。这两种受体都属于拟南芥富含亮氨酸重复序列受体激酶（LRR-RKs）的>200元蛋白质家族。FLS 2和EFR参与激活共同的细胞内信号输出，并且它们属于LRR-RKs的相同亚家族，共享结构特征，如在LRR中组织的细胞内激酶结构域和胞外域。然而，在氨基酸序列水平上，它们仅
FLS2 and EFR are pattern recognition receptors in Arabidopsis thaliana perceiving the bacterial proteins flagellin and Elongation factor Tu (EF-Tu). Both receptors belong to the >200 membered protein family of Leucine-Rich Repeat Receptor Kinases (LRR-RKs) in Arabidopsis. FLS2 and EFR are engaged in the activation of a common intracellular signal output and they belong to the same subfamily of LRR-RKs, sharing structural features like the intracellular kinase domain and the ectodomain organized in LRRs. On the amino acid sequence level, however, they are only