Antimicrobial resistance in organisms causing diarrheal disease
Antimicrobial resistance in organisms causing diarrheal disease
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DOI：
10.1093/clinids/24.supplement_1.s102
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发表时间：
1997-01-01
影响因子：
11.8
通讯作者：
Khan, EH
中科院分区：
文献类型：
--
作者：
Sack, RB;Rahman, M;Khan, EH
抗微生物耐药性在肠道感染的治疗中变得越来越重要，特别是那些由于志贺氏菌、霍乱弧菌、产肠毒素大肠杆菌（与旅行者腹泻相关）和伤寒沙门氏菌引起的肠道感染。发展中国家的抗菌药物耐药性最高，在那里抗菌药物的使用相对不受限制。最直接的问题是需要一种有效的，廉价的抗菌剂，可以安全地用于治疗由于志贺氏菌，主要是志贺氏菌1型痢疾的幼儿。
Antimicrobial resistance is becoming increasingly important in the treatment of enteric infections, particularly those due to Shigella, Vibrio cholerae, enterotoxigenic Escherichia coli (associated with traveler's diarrhea), and Salmonella typhi. The rate of antimicrobial resistance is highest in the developing world, where the use of antimicrobial drugs is relatively unrestricted. Of greatest immediate concern is the need for an effective, inexpensive antimicrobial that can be used safely as treatment for small children with dysentery due to Shigella, primarily Shigella dysenteriae type 1.