Effects of Neuropeptides on Mucociliary Activity
Effects of Neuropeptides on Mucociliary Activity
复制标题
神经肽对粘膜纤毛活动的影响
DOI：
10.1177/000348948609500120
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
U. Mercke
中科院分区：
文献类型：
--
作者：
S. Lindberg;J. Hybbinette;U. Mercke
The effects of four neuropeptides, vasoactive intestinal polypeptide, enkephalin, bombesin, and substance P, on mucociliary activity in the rabbit maxillary sinus were investigated in vivo. The peptides were administered via the feeding artery (arteria maxillaris), and the resulting effects were registered with a noninvasive photoelectric technique. The peptides were tested in the dose range 0.0001 to 10 μg/kg body weight. The following results were observed: 1) vasoactive intestinal polypeptide and enkephalin did not influence mucociliary activity; 2) bombesin had only a slight accelerating effect on the mucociliary activity at doses of 0.1 to 10 μg/kg; and 3) substance P markedly accelerated the mucociliary activity in a dose-dependent manner in the dose range 0.01 to 10 μg/kg, the maximal increase being about 50%. The effect of substance P was atropine-resistant, and probably acted directly on the mucosa.
过敏反应化学介质对纤毛功能的影响。
DOI：
10.1016/0091-6749(83)90626-7
发表时间：
1983
期刊：
The Journal of allergy and clinical immunology
影响因子：
--
作者：
Wanner,A;Maurer,D;Abraham,WM;Szepfalusi,Z;Sielczak,M
通讯作者：
Sielczak,M