CASE REPORT: Effect of Steroid Therapy for Late Dumping Syndrome After Total Gastrectomy: Report of a Case
CASE REPORT: Effect of Steroid Therapy for Late Dumping Syndrome After Total Gastrectomy: Report of a Case
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病例报告：类固醇治疗对全胃切除术后晚期倾倒综合征的效果：病例报告
DOI：
10.1023/b:ddas.0000030092.08039.db
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发表时间：
2004
影响因子：
3.1
通讯作者：
H. Naito
中科院分区：
文献类型：
--
作者：
C. Shibata;Y. Funayama;K. Fukushima;K. Shiiba;I. Sasaki;K. Itoi;H. Naito
晚倾综合征，或所谓的“反应性低血糖”，是一种罕见的疾病，发生在进食后1-3小时，似乎是由于对糖的快速吸收而发生的高胰岛素血症的反应而引起的（1）。该综合征的发病机制尚未完全了解。虽然饮食调整通常可有效预防低血糖，但有些患者对这些饮食控制和药物（如阿卡波糖、二氮嗪和生长抑素类似物）难以耐受，这些药物被认为对晚期倾倒综合征有效（1-4）。我们报告一位对这些治疗无效的晚期倾倒综合征患者，他成功地用口服泼尼松龙预防低血糖。
Late dumping syndrome, or so-called “reactive hypoglycemia,” is a rare disorder that occurs 1–3 hr after ingestion of a meal and appears to be caused in response to the hyperinslinemia that occurs with the rapid absorption of sugar (1). The pathogenesis of this syndrome is not well understood. Although dietary modifications are often effective in preventing hypoglycemia, some patients are refractory to these dietary manipulations and medications such as acarbose, diazoxide, and somatostatin analogue believed to be effective for late dumping syndrome (1–4). We report a patient with late dumping syndrome unresponsive to these treatments who was successfully treated with oral prednisolone to prevent hypoglycemia.