Luminaolide, a novel metamorphosis-enhancing macrodiolide for scleractinian coral larvae from crustose coralline algae

Luminaolide, a novel metamorphosis-enhancing macrodiolide for scleractinian coral larvae from crustose coralline algae
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DOI:
10.1016/j.tetlet.2009.09.065
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发表时间:
2009-11-25
影响因子:
1.8
通讯作者:
Uemura, Daisuke
Uemura, Daisuke
中科院分区:
化学4区
文献类型:
--
作者:
Kitamura, Makoto;Schupp, Peter J.;Uemura, Daisuke

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从硬壳珊瑚藻类(CCA)中分离得到一种新的变态增强型Maciodiokin,LIGNOLALID(1)。经光谱分析确定其结构为:用80%甲醇水溶液洗脱的部分(130mU g/m L),用相同的CCA提取物的ODS凝胶柱层析法诱导幼虫变态(25.9+/-74%),其中1(25.6 ng/m L)(C)2009 Elsevier Ltd.的变态诱导活性进一步提高到92.6+/-29%。
A new metamorphis-enhancing maciodiohide, luminaolide (1), was isolated from the crustose coralline algae (CCA) Hydrolithon reinboldn. Its structure was determined by spectroscopic analysis A fraction (130 mu g/mL) eluted with 80% aqueous MeOH by ODS gel column chromatography of the same CCA extract induced larval metamorphosis (25.9 +/- 74%) against Leptastrea purpurea, and its metamorphosis-inducing activity was further enhanced to 92.6 +/- 29% with the addition of 1 (25.6 ng/mL) (C) 2009 Elsevier Ltd. All rights reserved