History matters: illuminating metaplasticity in the developing brain.

History matters: illuminating metaplasticity in the developing brain.
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历史很重要:阐明大脑发育中的化塑性。

DOI:
10.1016/j.neuron.2009.10.012
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发表时间:
2009
期刊:
影响因子:
16.2
通讯作者:
Tao,HuizhongWhit
Tao,HuizhongWhit
中科院分区:
医学1区
文献类型:
--
作者:
Wang,Sheng-Zhi;Tao,HuizhongWhit

文献摘要

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亚可塑性是指神经元可塑性状态的活动依赖性调节。在本期《神经元》中,Dunfield和哈斯证明,在完整发育的大脑回路中,视觉刺激的特定模式驱动个体神经元的功能可塑性,其结果是可变的,这些神经元受到视觉训练后的时间平均突触后活动的影响。
Metaplasticity refers to an activity-dependent regulation of the plastic state of neurons. In this issue ofNeuron, Dunfield and Haas demonstrate that in intact developing brain circuits, specific patterns of visual stimulation drive functional plasticity of individual neurons with variable outcomes, predisposed by time-averaged postsynaptic activity recent to visual training.