Multi-vendor multi-site T(1ρ) and T(2) quantification of knee cartilage.
Multi-vendor multi-site T(1ρ) and T(2) quantification of knee cartilage.
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DOI：
10.1016/j.joca.2020.07.005
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发表时间：
2020-12
影响因子：
7
通讯作者：
Li X
中科院分区：
文献类型：
--
作者：
Kim J;Mamoto K;Lartey R;Xu K;Nakamura K;Shin W;Winalski CS;Obuchowski N;Tanaka M;Bahroos E;Link TM;Hardy PA;Peng Q;Reddy R;Botto-van Bemden A;Liu K;Peters RD;Wu C;Li X
在多个供应商的MR系统上开发基于相同序列结构的3D T1ρ和T2成像，并评估膝关节软骨T1、ρ和T2测量的站点内重复性和站点间重复性。在西门子、GE和飞利浦的MR系统上实现了三维磁化准备的角度调制分区k空间破坏梯度回波快照(3DMAPSS)。使用来自三家供应商的3T磁共振系统在四个地点收集了幻影和人类受试者的数据，并采用了统一的协议。通过线圈的不同位置采集体模数据。志愿者在重新定位后又进行了扫描和重新扫描。两名旅行志愿者在所有地点进行了扫描。数据被转移到一个地点进行集中处理。模体内平均变异系数T1ρ为1.09%~3.05%，T2为1.78%~3.30%；志愿者T1ρ为1.60%~3.93%，T2为1.44%~4.08%。在体模中，MAPSST1、ρ和T2的点间平均变异系数分别为5.23%和6.45%；在志愿者中，MAPSST1、ρ和T2的点间平均CV分别为8.14%和10.06%。这项研究显示了膝关节软骨中T1、ρ和T2值的多部位、多供应商重复性的良好结果。这些定量方法可应用于具有受控序列结构和扫描参数以及集中数据处理的大规模多点、多供应商试验。
To develop 3D T1ρ and T2 imaging based on the same sequence structure on MR systems from multiple vendors, and to evaluate intra-site repeatability and inter-site inter-vendor reproducibility of T1ρ and T2 measurements of knee cartilage. 3D magnetization-prepared angle-modulated partitioned k-space spoiled gradient echo snapshots (3D MAPSS) were implemented on MR systems from Siemens, GE and Philips. Phantom and human subject data were collected at four sites using 3T MR systems from the three vendors with harmonized protocols. Phantom data were collected by means of different positioning of the coil. Volunteers were scanned and rescanned after repositioning. Two traveling volunteers were scanned at all sites. Data were transferred to one site for centralized processing. Intra-site average coefficient of variations (CVs) ranged from 1.09% to 3.05% for T1ρ and 1.78% to 3.30% for T2 in phantoms, and 1.60% to 3.93% for T1ρ and 1.44% to 4.08% for T2 in volunteers. Inter-site average CVs were 5.23% and 6.45% for MAPSS T1ρ and T2, respectively in phantoms, and 8.14% and 10.06% for MAPSS T1ρ and T2, respectively, In volunteers. This study showed promising results of multi-site, multi-vendor reproducibility of T1ρ and T2 values in knee cartilage. These quantitative measures may be applied in large-scale multi-site, multi-vendor trials with controlled sequence structure and scan parameters and centralized data processing.
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影响因子：
3.3
作者：
Foltz, WD;Stainsby, JA;Wright, GA
通讯作者：
Wright, GA
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3.3
作者：
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2.2
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影响因子：
3.3
作者：
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影响因子：
7
作者：
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通讯作者：
Link, T. M.