Hemodynamic changes in the right ventrolateral prefrontal cortex relate to the psychological mood profile
Hemodynamic changes in the right ventrolateral prefrontal cortex relate to the psychological mood profile
复制标题
DOI：
10.1016/j.neulet.2022.136653
复制
发表时间：
2022-04
影响因子：
2.5
通讯作者：
Kenji Tsuchiya;Kaori Shimoda;Shinichi Mitsui;Noriki Yamaya;Senichiro Kikuchi;Takaaki Fujita;F. Tozato
中科院分区：
文献类型：
--
作者：
Kenji Tsuchiya;Kaori Shimoda;Shinichi Mitsui;Noriki Yamaya;Senichiro Kikuchi;Takaaki Fujita;F. Tozato
先前的研究表明，右腹外侧前额叶皮层（VLPFC）参与情绪调节。然而，大多数此类研究是在非生理条件下进行的，如经颅直流电或重复经颅磁刺激。我们已经证明，右侧VLPFC会受到剧烈的日常活动的刺激，比如打扫卫生。在这里，我们用这个系统研究了右VLPFC和情绪变化之间的关系。14名年轻人分别在不同的日子里用吸尘器清扫地板，并保持站立的姿势作为控制任务。在任务过程中测量前额皮质的氧合血红蛋白（oxy-Hb）和脱氧血红蛋白（deoxy-Hb）信号。在实验前后分别测量情绪状态量表（POMS）和二维情绪量表（TDMS）的得分。两个量表中任务前和任务后的子量表得分差异计算为ΔPOMS和ΔTDMS。清洁任务显著增加了双侧VLPFC和右侧额极的氧- hb信号，但不影响脱氧- hb信号。对照任务显著降低了部分脑区氧- hb信号。在清理任务后，POMS的困惑-困惑得分发生了变化。重要的是，右侧VLPFC中的氧- hb信号与ΔPOMS混淆-困惑评分呈负相关。清理任务刺激的右侧VLPFC的活动可能与困惑-困惑情绪状态有关。
Previous reports indicate that the right ventrolateral prefrontal cortex (VLPFC) is involved in emotional regulation. However, most such studies were performed under unphysiological conditions, like the administration of transcranial direct current or repetitive transcranial magnetic stimulation. We have shown that the right VLPFC is stimulated by an acute bout of daily activity, such as cleaning. Here, we investigated the relationship between the right VLPFC and mood changes using this system. Fourteen young adults vacuumed a floor as a cleaning task and kept a standing position as a control task on separate days. The oxyhemoglobin (oxy-Hb) and deoxy-hemoglobin (deoxy-Hb) signals of the prefrontal cortex were measured during the tasks. The mood scale scores of Profile of Mood States 2nd edition (POMS) and Two-Dimensional Mood Scale (TDMS) were measured before and after both tasks. The differences in subscale scores between pre- and post-tasks in both scales were calculated as ΔPOMS and ΔTDMS. The cleaning task significantly increased the oxy-Hb signal in the bilateral VLPFC and right frontopolar, but did not affect the deoxy-Hb signals. The control task significantly decreased the oxy-Hb signal in some brain regions. The Confusion–Bewilderment score in POMS changed after the cleaning task. Importantly, the oxy-Hb signal in the right VLPFC was negatively correlated with the ΔPOMS Confusion–Bewilderment score. The activity of the right VLPFC stimulated by the cleaning task might have a correlation with the Confusion–Bewilderment mood state.