Smoking patterns and outcomes in a population of pregnant women with other substance use disorders
Smoking patterns and outcomes in a population of pregnant women with other substance use disorders
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DOI：
10.1080/14622200802097548
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发表时间：
2008-01-01
影响因子：
4.7
通讯作者：
Wallace, Cate
中科院分区：
文献类型：
--
作者：
Burns, Lucy;Mattick, Richard P.;Wallace, Cate
采用回溯性横断面研究设计，我们调查了被诊断为妊娠期药物使用障碍的母亲所生婴儿的吸烟模式和相关的新生儿结局。产前和分娩入院与助产士在五年期间(1998-2002年)关于怀孕护理、服务和结局的数据有关。如果出生入院或任何怀孕入院涉及大麻、阿片类药物、兴奋剂或酒精相关的ICD-10AM代码，则出生入院被标记为吸毒阳性。有4346名孕妇在怀孕期间被诊断为与物质相关的活产。有物质相关诊断的妇女(药物组)与无物质相关诊断的妇女(非药物组)相比，在孕期吸烟的调整优势比为10.8(95%CI=9.9-11.7)。吸毒组的女性吸烟量也更大；26%的女性每天吸烟1-10支，56%的女性每天吸烟超过10支，而在非吸毒组中，这两组女性的这一比例均为8%。相对于药物组，非药物组孕期戒烟的调整优势比为3.1(95%CI=2.3~4.3)。在药物组的女性中，任何吸烟都显著增加了胎儿发育不良、早产和进入特殊护理托儿所的风险。总之，创新和有效的戒烟战略应将孕妇作为高度优先事项。进一步的研究应该确定最适合在怀孕期间使用其他物质的女性的戒烟模式。
Using a retrospective cross-sectional study design, we examined smoking patterns and associated neonatal outcomes in infants born to women with a diagnosis of a substance use disorder in pregnancy. Antenatal and birth admissions were linked to midwives data on pregnancy care, services, and outcomes over a 5-year period (1998-2002). Birth admissions were flagged as positive for drug use where a birth admission or any pregnancy admission for that birth involved a cannabis-, opioid-, stimulant-, or alcohol-related ICD-10AM code. There were 4,346 live births to women with a substance-related diagnosis in pregnancy. Women with a substance-related diagnosis (the drug group) had an adjusted odds ratio for smoking during pregnancy of 10.8 (95% CI=9.9-11.7) relative to women without a substance-related diagnosis (the non-drug group). Women in the drug group also were heavier smokers; 26% smoked 1-10 cigarettes/day and 56% smoked more than 10 cigarettes/day compared with 8% in both groups in the non-drug group. Relative to the drug group, the adjusted odds ratio for quitting smoking during pregnancy in the non-drug group was 3.1 (95% CI=2.3-4.3). Among women in the drug group, any smoking significantly increased the risk of poor fetal growth, prematurity, and admission to the special care nursery. In conclusion, innovative and effective strategies for tobacco cessation should target pregnant women as a high priority. Further research should identify the models of tobacco cessation most suited to women who also use other substances during pregnancy.