Highly sensitive and selective detection of nitrite ions using Fe3O4@SiO2/Au magnetic nanoparticles by surface-enhanced Raman spectroscopy
Highly sensitive and selective detection of nitrite ions using Fe3O4@SiO2/Au magnetic nanoparticles by surface-enhanced Raman spectroscopy
复制标题
DOI：
10.1016/j.bios.2016.05.068
复制
发表时间：
2016-11-15
影响因子：
12.6
通讯作者：
Nugen, Sam R.
中科院分区：
文献类型：
--
作者：
Chen, Juhong;Pang, Shintaro;Nugen, Sam R.
利用Fe3O4@SiO2/Au磁性纳米粒子（MNP）表面增强拉曼散射（Sers）技术，建立了一种检测亚硝酸根离子浓度的新方法。所制备的双功能纳米复合材料可用于同时使用外部磁场纯化目标分子并产生具有痕量水平的目标分子的拉曼指纹光谱。在酸性介质中，亚硝酸根离子引发Fe3O4@SiO2/Au MNP上的4-氨基苯硫酚（4-ATP）分子形成偶氮键，在Sers谱上产生3个新的标记峰。在优化的条件下，基于三个标志物峰的检测限分别为15.63，13.69和17.77 μ M，远低于美国环境保护署（EPA）定义的饮用水中允许的最大NO2-浓度1.0 mg L-1（71.4 μ M）。该方法检测亚硝酸根离子的特异性被证明使用常见离子作为竞争对手。此外，基于SERS的技术被成功地用于检测亚硝酸根离子在池塘水，合成的尿液，和泡菜盐水。该方法灵敏度高，选择性好，不需预处理，适用于真实的样品中亚硝酸根离子的检测。(C)2016爱思唯尔B. V.保留所有权利。
A novel and pragmatic method was developed to detect the concentration of nitrite ions using Fe3O4@SiO2/Au magnetic nanoparticles (MNPs) by surface-enhanced Raman scattering (SERS). The as prepared bifunctional nanocomposites can be used to simultaneously purify target molecules using external magnetic field and produce Raman fingerprint spectrum with trace level of target molecules. In acidic media, 4-aminothiophenol (4-ATP) molecules conjugated on Fe3O4@SiO2/Au MNPs were triggered by nitrite ions to form azo bonds, resulting in three new marker peaks on the SERS spectrum. Under optimized conditions, the detection limit based on the three marker peaks were 15.63, 13.69, and 17.77 mu M, which was much lower than the maximum NO2- concentration of 1.0 mg L-1 (71.4 mu M) allowed in drinking water as defined by U.S. Environmental Protection Agency (EPA). The specificity of this proposed method to detect nitrite ions was demonstrated using common ions as competitors. In addition, the SERS-based technique was successfully employed to detect nitrite ions in pond water, a synthetic urine solution, and pickle brine. Considering its good sensitivity and selectivity, the detection method is well suited for the detection of nitrite ions in real samples without pretreatment steps. (C) 2016 Elsevier B.V. All rights reserved.