Encapsulating Peritoneal Sclerosis in the New Millennium: A National Cohort Study
Encapsulating Peritoneal Sclerosis in the New Millennium: A National Cohort Study
复制标题
DOI：
10.2215/cjn.01260209
复制
发表时间：
2009-07-01
影响因子：
9.8
通讯作者：
Mactier, Robert A.
中科院分区：
文献类型：
--
作者：
Brown, Michaela C.;Simpson, Keith;Mactier, Robert A.
背景和目标：该研究的目的是建立发病率和所有封装腹膜硬化症（EPS）的情况下，腹膜透析（PD）治疗的患者的特点设计，设置，参与者，和测量：患者队列，开始PD从2000年1月1日，2007年12月31日，从苏格兰肾脏登记处（n = 1238）。可能的EPS病例由10个成人苏格兰肾脏单位确定。患者的记录进行了检查，以确保病例符合诊断标准。结果：四十六例被确定，19个有他们的第一次PD暴露后，2000年1月1日。发生率为1.5%，发生率为4.9/1000人-年。发病率随着PD持续时间的增加而增加，在PD暴露2至3年、>3至4年、>4至5年、>5至6年和>6年时，发病率分别为0、0.6、2.0、3.5、8.1、8.8和5%。EPS病例的中位PD持续时间为5.1年（四分位距[IQR] 3.4 - 6.1年）。诊断时，12例（26%）处于PD状态，33例（72%）被诊断为
Background and objectives: The study aim was to establish the incidence and characterize all encapsulating peritoneal sclerosis (EPS) cases in patients treated by peritoneal dialysis (PD).Design, setting, participants, & measurements: The patient cohort, which started PD from January 1, 2000, to December 31, 2007, was identified from the Scottish Renal Registry (n = 1238). Possible EPS cases were identified by the ten adult Scottish renal units. Patient records were examined to ensure cases met diagnostic criteria.Results: Forty-six cases were identified; 19 had their first PD exposure after January 1, 2000. The rate was 1.5%, an incidence of 4.9 per 1000 person-years. The incidence increased with PD duration, with rates of 0, 0.6, 2.0, 3.5, 8.1, 8.8 and 5% at 2 to 3, >3 to 4, >4 to 5, >5 to 6 and >6 yr PD exposure, respectively. The median PD duration of EPS cases was 5.1 yr (interquartile range [IQR] 3.4 to 6.1 yr). At diagnosis, 12 (26%) were on PD and 33 (72%) were diagnosed