Risk of Bias in Reports of In Vivo Research: A Focus for Improvement
Risk of Bias in Reports of In Vivo Research: A Focus for Improvement
复制标题
DOI：
10.1371/journal.pbio.1002273
复制
发表时间：
2015-10-01
期刊：
影响因子：
9.8
通讯作者：
Sena, Emily S.
中科院分区：
文献类型：
--
作者：
Macleod, Malcolm R.;McLean, Aaron Lawson;Sena, Emily S.
实验结果的可靠性取决于实验设计的严谨性。在这里，我们显示有限的报告措施，以减少偏倚风险的随机样本的生命科学出版物，显着较低的报告随机化的工作发表在期刊上的影响，和非常有限的报告措施，以减少偏倚风险的出版物从领先的英国机构。确定机构之间的差异既可以作为研究质量的衡量标准，也可以作为机构努力提高研究质量的工具。
The reliability of experimental findings depends on the rigour of experimental design. Here we show limited reporting of measures to reduce the risk of bias in a random sample of life sciences publications, significantly lower reporting of randomisation in work published in journals of high impact, and very limited reporting of measures to reduce the risk of bias in publications from leading United Kingdom institutions. Ascertainment of differences between institutions might serve both as a measure of research quality and as a tool for institutional efforts to improve research quality.