Establishment of conditioned taste aversions with a 24-hour CS-US interval
Establishment of conditioned taste aversions with a 24-hour CS-US interval
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以 24 小时 CS-US 间隔建立条件性味觉厌恶
DOI：
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发表时间：
1973
期刊：
影响因子：
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通讯作者：
Ronald Stephens
中科院分区：
文献类型：
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作者：
F. Etscorn;Ronald Stephens
进行了两项实验，研究 24 小时 CS-US 间隔对味觉厌恶学习的影响。在第一个实验中，雄性白化大鼠被允许饮用非首选的 CS（盐酸味水），并在 24 小时后腹腔注射一种诱发疾病的药物（环磷酰胺）。经过两次这样的配对后，动物表现出了对加味水的厌恶。在实验 II 中，雌性大鼠在饮用首选 CS（糖精味水）后 24 小时暴露于相同的 US 中。然而，仅经过一次这样的配对后，实验组在两瓶选择的情况下就避免了加味水，而更喜欢普通自来水，而注射盐水的对照组则更喜欢糖精味水而不是普通自来水。由于长时间延迟强化的条件反射存在争议，因此对雄性大鼠进行了实验 II 的系统复制，并再次建立了对糖精味水的厌恶。
Two experiments were conducted investigating the effects of a 24-h CS-US interval in taste aversion learning. In the first experiment, male albino rats were allowed to consume a nonpreferred CS (HCL-flavored water) and injected, intraperitoneally, 24 h later with an illness-inducing drug (cyclophosphamide). After two such pairings, the animals exhibited an aversion to the flavored water. In Experiment II, female rats were exposed to the same US 24 h following consumption of a preferred CS (saccharin-flavored water). However, after only one such pairing, experimental Ss avoided the flavored water and preferred normal tap water in a two-bottle choice situation, while saline-injected controls preferred the saccharin-flavored water to the plain tap water. Due to the controversial nature of conditioning with such long delays of reinforcement, a systematic replication of Experiment II was conducted with male rats, and again an aversion was established to the saccharin-flavored water.