A highly selective and sensitive "turn-on" fluorescence chemodosimeter for the detection of mustard gas.
A highly selective and sensitive "turn-on" fluorescence chemodosimeter for the detection of mustard gas.
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DOI：
10.1039/c4cc04801f
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发表时间：
2014-09
影响因子：
4.9
通讯作者：
D. Raghavender Goud;A. Purohit;Vijay Tak;D. K. Dubey;Pravin Kumar;Deepak Pardasani
中科院分区：
文献类型：
--
作者：
D. Raghavender Goud;A. Purohit;Vijay Tak;D. K. Dubey;Pravin Kumar;Deepak Pardasani
报道了一种新的化学剂量测定方法，该方法基于串联的S烷基化反应，然后罗丹明硫酰胺与芥子气发生脱硫反应。化学剂量计对硫芥等潜在的脱氧核糖核酸烷基化试剂具有很高的选择性，而不是其他简单的烷基卤化物，检测下限为4.75μM。
A new chemodosimetric protocol based on a tandem S-alkylation followed by desulfurisation reaction of rhodamine-thioamide with mustard gas is reported. The chemodosimeter is highly selective for potential DNA alkylating agents like sulfur mustard, over other simple alkyl halides with the limit of detection of 4.75 μM.