Epiphora caused by conjunctivochalasis - Treatment with transplantation of preserved human amniotic membrane
Epiphora caused by conjunctivochalasis - Treatment with transplantation of preserved human amniotic membrane
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DOI：
10.1097/00003226-200108000-00012
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发表时间：
2001-08-01
期刊：
影响因子：
2.8
通讯作者：
Terzidou, CD
中科院分区：
文献类型：
--
作者：
Georgiadis, NS;Terzidou, CD
目的.目的探讨保存人羊膜在结膜松弛症所致溢泪中的应用。方法. 12名患者，7名女性和5名男性，年龄从56岁到72岁（平均61岁），被转介到我们的角膜服务与慢性溢泪。所有患者均无泪点外翻，泪道通畅，染料消失试验异常。所有患者均已接受各种治疗，包括多次泪道冲洗、抗生素滴眼液、类固醇滴眼液和人工泪液滴眼液。在所有患者中，结膜松弛，这是以前没有诊断，裂隙灯检查是明显的。手术切除多余结膜后，将保存的人羊膜置于其上，并用10-0尼龙连续缝线缝合至游离结膜边缘。在术后期间，应用人工泪液和类固醇/抗生素滴剂。结果从术后第一天起，溢泪明显改善。术后10 ~ 15天（平均12天）拆线后，无患者主诉溢泪。染料消失试验正常。随访6 ~ 11个月，平均8个月，无一例出现溢泪，羊膜移植区未见结膜松弛。结论在我们的经验中，保存人羊膜移植大大改善了结膜松弛症引起的溢泪症状。需要对普通眼科医生进行关于这种情况的继续教育。
Purpose. To present our experience with the use of preserved human amniotic membrane on patients with epiphora caused by conjunctivochalasis. Methods. Twelve patients, seven women and five men, ages ranging from 56 to 72 years (mean, 61 years) were referred to our Cornea Service with chronic epiphora. In all patients, no punctal ectropion was present, the lacrimal pathway was patent, and the dye disappearance test was abnormal. All patients had already undergone various therapies including multiple irrigations of the lacrimal system, antibiotic drops, steroid drops, and artificial tear drops. In all patients, conjunctivochalasis, which was not previously diagnosed, was evident on slit-lamp examination. After surgical removal of the excess conjunctiva, preserved human amniotic membrane was placed over and sutured with 10-0 nylon continuous suture to the free conjunctival edges. During the postoperative period, artificial tear drops and steroid/antibiotic drops were applied. Results. Improvement of the epiphora was evident from the first postoperative day. After removal of the suture 10 to 15 days (mean, 12 days) after surgery, no patient complained of epiphora. The dye disappearance test was normal. During the follow-up period, which ranged from 6 to 11 months (mean, 8 months), no patient complained of epiphora and no conjunctivochalasis was detected in the area in which human amniotic membrane was transplanted. Conclusion. In our experience, transplantation of preserved human amniotic membrane greatly improved symptoms of epiphora caused by conjunctivochalasis. Continued education of the general ophthalmologists concerning this condition is required.