Early Enteral Nutrition With Polymeric Feeds Was Associated With Chylous Ascites in Patients With Severe Acute Pancreatitis
Early Enteral Nutrition With Polymeric Feeds Was Associated With Chylous Ascites in Patients With Severe Acute Pancreatitis
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聚合饲料的早期肠内营养与重症急性胰腺炎患者的乳糜腹水有关
DOI：
10.1097/mpa.0000000000000067
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发表时间：
2014-05
期刊：
影响因子：
2.9
通讯作者：
Zhang Yun
中科院分区：
文献类型：
--
作者：
Yu Wenqiao;Wang Zhien;Chen Zuobing;Zhang Yun
目的乳糜腹水（CA）可能参与了重症急性胰腺炎（SAP）的病理过程，但其机制尚不清楚。本研究旨在探讨SAP患者CA的发生率及其与肠内营养（EN）的关系。方法回顾性分析85例SAP患者的临床资料。将SAP发病后72小时内开始EN的患者分为早期EN（EEN）组，其他患者分为晚期EN组。采用聚合物配方或半元素饲料营养制剂，观察早期肠内营养组和后期肠内营养组的CA发生率和预后。结果85例患者中13例（15.29%）为CA。接受聚合物配方的EEN患者中CA的发生率较高（9/33，P < 0.05）。所有CA患者均采用改良中链甘油三酯饮食成功治疗。因此，有或无CA的患者在重症监护病房的住院时间和死亡率方面没有差异。结论SAP患者早期肠内喂养高分子配方奶粉可增加CA的发生率。未来的研究是必要的，以证实我们的研究结果，并评估更好的肠道喂养的选择，以避免CA。
Objective Chylous ascites (CA) may be involved in the pathological process of severe acute pancreatitis (SAP), but the underlying mechanisms remain unknown. This study investigated the incidence of CA in patients with SAP and its relationship with enteral nutrition (EN). Methods A retrospective review of 85 patients with SAP admitted to our hospital was performed. Patients starting EN within 72 hours after the onset of SAP were classified as the early EN (EEN) group, and others, as the later EN group. The incidences of CA and prognosis in the EEN and later EN groups were examined with nutrition preparation of polymeric formula or semielemental feed. Results Thirteen (15.29%) of 85 patients were identified with CA. A higher incidence of CA was observed in EEN patients who received polymeric formula (9 of 33, P < 0.05). All patients with CA were successfully treated with a modified medium-chain triglyceride diet. Consequently, there were no differences in intensive care unit stay and in mortality rates in patients with or without CA. Conclusions There was a higher incidence of CA associated with early enteral feeding of polymeric formula in patients with SAP. Future studies are warranted to confirm our findings and evaluate better enteral feeding options to avoid CA.
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入院 48 小时内肠内营养通过减少并发症改善急性胰腺炎的临床结果：荟萃分析
影响因子：
3.7
作者：
Li, Jie-Yao;Yu, Tao;Chen, Qi-Kui
通讯作者：
Chen, Qi-Kui
影响因子：
4.3
作者：
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通讯作者：
Farrell, Stephen
影响因子：
1.2
作者：
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通讯作者：
Xia, Bing
DOI：
10.1016/s0002-9629(15)40594-4
发表时间：
1999-08
期刊：
The American journal of the medical sciences
影响因子：
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作者：
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通讯作者：
H. Ben-Ami;P. Nagachandran;A. Assalia;Y. Edoute
影响因子：
3.1
作者：
Al-Ghamdi, Mohammed Y.;Bedi, Anil;Peltekian, Kevork M.
通讯作者：
Peltekian, Kevork M.