Are dendritic cells the key to liver transplant tolerance?
Are dendritic cells the key to liver transplant tolerance?
复制标题
树突状细胞是肝移植耐受的关键吗?
DOI:
10.1016/s0167-5699(98)01378-4
复制
发表时间:
1999
期刊:
影响因子:
--
通讯作者:
Lu,L
中科院分区:
文献类型:
--
作者:
Thomson,AW;Lu,L
The inherent tolerogenicity of liver allografts could be due to the organ's combination of hematopoietic activity, production of growth-promoting and immunoregulatory cytokines, and comparatively large numbers of potentially tolerogenic antigen-presenting cells, in particular dendritic cells (DCs). Here, Angus Thomson and Lina Lu consider the evidence that DCs can subvert allogeneic T-cell responses and might be exploited therapeutically to prolong graft survival.