Dielectric modulation of biological water -: art. no. 228104
Dielectric modulation of biological water -: art. no. 228104
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DOI：
10.1103/physrevlett.93.228104
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发表时间：
2004-11-26
影响因子：
8.6
通讯作者：
Berry, RS
中科院分区：
文献类型：
--
作者：
Despa, F;Fernández, A;Berry, RS
我们发现，水受到邻位疏水体的约束，经历了一个librational动力学，降低了介电敏感性，并引起了“红移”的弛豫频率在水化壳。这些结果揭示了蛋白质在折叠或结合时增强分子内相互作用的方式。
We show that water constrained by vicinal hydrophobes undergoes a librational dynamics that lowers the dielectric susceptibility and induces a "redshift" of the relaxation frequency in the hydration shell. The results shed light on the way proteins enhance their intramolecular interactions as they fold or associate.