N-Sulfonyl hydroxamate derivatives as inhibitors of class II fructose-1,6-diphosphate aldolase
N-Sulfonyl hydroxamate derivatives as inhibitors of class II fructose-1,6-diphosphate aldolase
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DOI：
10.1016/j.bmcl.2005.09.006
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发表时间：
2005-12-15
影响因子：
2.7
通讯作者：
Blonski, C
中科院分区：
文献类型：
--
作者：
Gavalda, S;Braga, R;Blonski, C
Dihydroxyacetone-phosphate and phosphonate derivatives were synthesized bearing a N-sulfonyl hydroxamate moiety. The phosphate derivatives represent competitive inhibitors for the class II-FBP aldolase catalyzed reaction, while the phosphonate isosteres are comparatively weaker inhibitors. (c) 2005 Elsevier Ltd. All rights reserved.
