Prevalence of diagnosed and undiagnosed diabetes mellitus and its risk factors in a population-based study of Qatar
Prevalence of diagnosed and undiagnosed diabetes mellitus and its risk factors in a population-based study of Qatar
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DOI：
10.1016/j.diabres.2009.02.003
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发表时间：
2009-04-01
影响因子：
5.1
通讯作者：
Wareham, Nick J.
中科院分区：
文献类型：
--
作者：
Bener, Abdulbari;Zirie, Mahmoud;Wareham, Nick J.
目的：该研究的目的是确定诊断和未诊断的糖尿病、糖尿病前期的患病率，并确定卡塔尔成年人口样本中的相关危险因素。设计：这是一项横断面研究。环境：调查在城市和半城市初级卫生保健中心进行。调查对象和方法：调查于2007年1月至2008年7月在20岁以上的卡塔尔国民中进行。在参与研究的1434名受试者中，1117名（77.9%）表示同意。面对面访谈采用结构化问卷，随后进行实验室测试。DM是根据WHO专家组定义的。糖尿病前期状态是基于空腹血糖受损或葡萄糖耐量受损的存在。结果：卡塔尔成人糖尿病总体患病率高（16.7%），其中确诊糖尿病（10.7%）和新确诊糖尿病（5.9%）。12.5%的患者被诊断为糖耐量（IGT）受损，1.3%的患者被诊断为空腹血糖受损，总共13.8%。卡塔尔女性患糖尿病的比例（53.2%）高于卡塔尔男性（46.8%），在40-49岁年龄组中达到高峰（31.2%）。总糖尿病和IGT的年龄特异性患病率随着年龄的增长而增加。卡塔尔成年糖尿病人群的危险因素显著增高：中心性肥胖（p < 0.001）、高血压（p < 0.001）、甘油三酯（p < 0.001）、高密度脂蛋白（p = 0.003）、代谢综合征（p < 0.001）、心脏病（p < 0.001）。吸烟习惯和糖尿病家族史是糖尿病的主要致病因素。中心性肥胖与卡塔尔男性和女性中较高的糖尿病和IFG患病率相关。结论：目前的研究发现，成人卡塔尔人口中糖尿病的患病率中等。卡塔尔成年人中糖尿病前期的高比例将在未来几年内增加糖尿病的患病率。吸烟习惯和糖尿病家族史是糖尿病的主要致病因素。糖尿病的早期诊断对于降低这些糖尿病相关疾病的风险具有重要意义。2009爱思唯尔爱尔兰有限公司版权所有。
Objective: The objective of the study was to determine the prevalence of diagnosed and undiagnosed diabetes, pre-diabetes and to identify the associated risk factors in the sample of adult Qatari population.Design: This was a cross-sectional study.Setting: The survey was carried out in urban and semi-urban primary health care centers.Subjects and methods: The survey was conducted from January 2007 to July 2008 among Qatari nationals above 20 years of age. Of the 1434 subjects who were approached to participate in the study, 1117 (77.9%) gave their consent. Face to face interviews were conducted using a structured questionnaire followed by laboratory tests. DM was defined according to the WHO expert group. Pre diabetes status was based on the presence of impaired fasting glucose or impaired glucose tolerance.Results: The overall prevalence of diabetes mellitus among adult Qatari population was high (16.7%) with diagnosed DM (10.7%) and newly diagnosed DM (5.9%). The impaired glucose tolerance (IGT) was diagnosed in 12.5%, while impaired fasting glucose was in 1.3% with a total of (13.8%). The proportion of DM was higher in Qatari women (53.2%) than in Qatari men (46.8%) and it peaked in the age group 40-49 years (31.2%). The age-specific prevalence of total DM and IGT increased with age. Risk factors were significantly higher in diabetic adult Qatari population: central obesity (p < 0.001), hypertension (p < 0.001), triglyceride (p < 0.001), HDL (p = 0.003), metabolic syndrome (p < 0.001), heart diseases (p < 0.001). Smoking habits and family history of DM were the major contributors for diabetes disease. The central obesity was associated with higher prevalence of DM and IFG among Qatari men and women.Conclusion: The present study has found a moderately high prevalence of diabetes mellitus in the adult Qatari population. High proportion of pre-diabetes in Qatari adults will increase the prevalence of DM in the next few years. Smoking habits and family history of DM were the major contributors for DM. Early diagnosis of DM is of major importance to reduce the risk of these diabetes-related conditions. (C) 2009 Elsevier Ireland Ltd. All rights reserved.