A Au(I)-catalyzed hydrogen bond-directed tandem strategy to synthesize indeno-chromen-4-one and indeno-quinolin-4-one derivatives
A Au(I)-catalyzed hydrogen bond-directed tandem strategy to synthesize indeno-chromen-4-one and indeno-quinolin-4-one derivatives
复制标题
Au(I)催化氢键定向串联策略合成茚并色烯-4-酮和茚并-喹啉-4-酮衍生物
DOI：
10.1039/c6cc05391b
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发表时间：
2016-01-01
影响因子：
4.9
通讯作者：
Cheng, Maosheng
中科院分区：
文献类型：
--
作者：
Jiang, Chongguo;Xiong, Zhiling;Cheng, Maosheng
提出了一种金催化氢键定向串联环化合成吲哚-铬-4- 1和吲哚-喹啉-4- 1衍生物的方法。羟基（或酰胺基）与羰基之间存在的氢键对控制选择性起着至关重要的作用，实验和理论证据都证实了这一点。
A gold-catalyzed hydrogen bond-directed tandem cyclization strategy to synthesize indeno-chromen-4-one and indeno-quinolin-4-one derivatives has been developed. The hydrogen bond existing between the hydroxyl group (or the amide group) and the carbonyl group played an essential role in controlling the selectivity, which was confirmed by both experimental and theoretical evidence.