Exposure to trauma: A comparison of cocaine-dependent cases and a community-matched sample
Exposure to trauma: A comparison of cocaine-dependent cases and a community-matched sample
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DOI：
10.1016/j.drugalcdep.2010.05.012
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发表时间：
2010-11-01
影响因子：
4.2
通讯作者：
Bierut, Laura Jean
中科院分区：
文献类型：
--
作者：
Afful, Stephanie E.;Strickland, Jaime R.;Bierut, Laura Jean
背景资料：本研究的目的是检查可卡因依赖的情况下，社区比较sample.Methods：参与者接受了采访，作为可卡因依赖的家庭研究的一部分，创伤性事件和创伤后应激障碍率。一项横断面病例队列设计评估了总共918名参与者：459名可卡因依赖病例来自化学依赖治疗，459名社区参与者。以社区为基础的比较参与者与可卡因依赖病例在出生年份（1年内），种族，性别和邻里（邮政编码）上相匹配。参与者完成了一个人的采访后，半结构化评估的遗传学的酒精中毒（SSAGA）。结果：相比社区为基础的个人，可卡因依赖的情况下，招募治疗经历了更高的攻击事件，包括强奸或性侵犯的妇女（58%比33%）和威胁与武器的男子（75%比52%）。可卡因依赖病例比社区参与者（4.64 vs. 3.08）和PTSD（22.4%和12.2%）遭受更多类型的创伤。创伤暴露的数量，目睹创伤给他人，经历暴力创伤，是女性的预测PTSD的条件风险，即使在控制可卡因依赖和其他人口factors.Conclusions：可卡因依赖与接触创伤事件和PTSD的风险增加密切相关，经历多重，暴力创伤增加PTSD的风险，无论可卡因依赖。在我们以社区为基础的参与者中看到的创伤的高患病率强调了邻里暴力的作用以及药物依赖、创伤暴露和创伤后应激障碍之间的联系。(C)2010爱思唯尔爱尔兰有限公司版权所有。
Background: The purpose of this study was to examine rates of traumatic events and PTSD in cocaine-dependent cases and a community comparison sample.Methods: Participants were interviewed as part of the Family Study of Cocaine Dependence. A cross-sectional case-cohort design assessed a total of 918 participants: 459 cocaine-dependent cases recruited from chemical dependency treatment and 459 community-based participants. Community-based comparison participants were matched to cocaine-dependent cases on year of birth (within 1 year), ethnicity, gender, and neighborhood (zip code). Participants completed a personal interview modeled after the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA).Results: Compared to community-based individuals, cocaine-dependent cases recruited from treatment experienced higher rates of assaultive events including rape or sexual assault in women (58% vs. 33%) and threatened with a weapon in men (75% vs. 52%). Cocaine-dependent cases endured significantly more types of trauma than the community-based participants (4.64 vs. 3.08) and PTSD (22.4% and 12.2%). The number of traumatic exposures, witnessing trauma to others, experiencing violent trauma, and being female were predictive of conditional risk of PTSD, even after controlling for cocaine dependence and other demographic factors.Conclusions: Cocaine dependence is strongly associated with an increased risk of exposure to traumatic events and PTSD, and experiencing multiple, violent traumas increases the risk of PTSD, regardless of cocaine dependence. The high prevalence of trauma seen in our community-based participants emphasizes the role of violence in the neighborhood and the connection between drug dependence, trauma exposure, and PTSD. (C) 2010 Elsevier Ireland Ltd. All rights reserved.