Canalization of development and the inheritance of acquired characters
Canalization of development and the inheritance of acquired characters
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DOI：
10.1038/150563a0
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发表时间：
1942-07-01
期刊：
影响因子：
64.8
通讯作者：
Waddington, CH
中科院分区：
文献类型：
--
作者：
Waddington, CH
除了标准的遗传和拉马克假说来解释适应性胼胝体的进化，三维的可能性建议，在进化过程中的环境刺激已被取代的内部遗传因素。通过外部刺激形成胼胝体必须在遗传控制下。在服从自然选择的生物体中发生的发育反应一般都是为了一个最终结果而进行的。野生型的恒定性必须被视为基因型对环境和遗传组成中微小变异的缓冲作用的证据。有可能的是，适应性反应可以被固定，而不需要等待突变的发生，在原始的遗传背景中。能够很好地模仿反应从而享有选择优势。
In addition to the standard genetic and Lamarckian hypotheses to explain the evolution of adaptive callosities, a 3d possibility is suggested that during the course of evolution the environmental stimulus has been superseded by an internal genetical factor. The formation of a callosity through external stimulation must be under genetic control. Developmental reactions as they occur in organisms submitted to natural selection are in general canalized for one end result. The constancy of the wildtype must be taken as evidence of the buffering of the genotype against minor variations not only in the environment but also in its genetic make-up. It is possible that an adaptive response can be fixed without waiting for the occurrence of a mutation which, in the original genetic background. mimics the response well enough to enjoy selective advantage.