Determination of the real standard distribution of susceptible strains in zone histograms
Determination of the real standard distribution of susceptible strains in zone histograms
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DOI：
10.1016/s0924-8579(03)00107-9
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发表时间：
2003-07-01
影响因子：
10.8
通讯作者：
Kronvall, G
中科院分区：
文献类型：
--
作者：
Kronvall, G
介绍了一种归一化电阻率解释方法--NRI法的步骤。通过其有前途的自动校准系统，该方法产生的细菌物种-抗生素组合的区域直径直方图的耐药性的区域断点。只要性能显示出良好的重现性和精密度，这些折点给出了标准化的耐药性解释，其与各个实验室选择的纸片试验标准品、纸片效价、使用的培养基、接种量等无关。该方法应作为设定“细菌学折点”或“流行病学折点”的工具进行进一步测试，用于计算比较目的的耐药率，例如在抗生素耐药性监测中，以及用于纸片扩散试验的质量控制。(C)2003年Elsevier Science B. V.和国际化疗学会。All rights reserved.
The procedure for NRI, a method for normalised resistance interpretation, is presented. By means of its promising autocalibration system the method generates zone breakpoints for resistance in zone diameter histograms for bacterial species-antibiotic combinations. These breakpoints give a normalised interpretation of resistance which is independent of disc test standard chosen, disc potency, medium used, inoculum size, etc. of the individual laboratory as long as the performance shows good reproducibility and precision. The method should be further tested as a tool for setting 'bacteriological breakpoints' or 'epidemiological breakpoints', for calculating resistance rates for comparative purposes, e.g. in antibiotic resistance surveillance, and for quality control of the disc diffusion test. (C) 2003 Elsevier Science B.V. and the International Society of Chemotherapy. All rights reserved.