The Rise in Mortality from Breast Cancer in Young Women: Trend Analysis in Brazil.

The Rise in Mortality from Breast Cancer in Young Women: Trend Analysis in Brazil.
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DOI:
10.1371/journal.pone.0168950
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发表时间:
2017
期刊:
影响因子:
3.7
通讯作者:
Pelloso SM
Pelloso SM
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Rocha-Brischiliari SC;Oliveira RR;Andrade L;Brischiliari A;Gravena AA;Carvalho MD;Pelloso SM

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乳腺癌是妇女癌症死亡的最常见原因。本研究的目的是分析巴西、巴西各地区和各州乳腺癌总死亡率的时间趋势。这是对1996年至2013年期间生活在巴西、巴西各地区和各州的妇女死于乳腺癌的时间序列进行的探索性研究,该时间序列载于死亡率信息系统。对于趋势分析,使用多项式回归模型,当估计模型获得的p值<0.05时,认为趋势显著。巴西妇女的乳腺癌死亡率呈上升趋势(平均每年上升0.18; p <0.001),但存在区域差异,特别是在20-49岁年龄组(每年0.07; p <0.001)。50-69岁年龄组保持不变,但平均发病率较高(37.14)。需要更有效的规划,以关注巴西各地区的不同情况。乳腺癌发病率和死亡率的筛查战略也必须根据该国的年龄组重新考虑。
Breast cancer is the most common cause of cancer death among women. The objective of this study was to analyze time trends in overall mortality from breast cancer in Brazil, Brazilian regions and States. This is an exploratory study, of the time series of deaths from breast cancer contained in the Mortality Information System (SIM), of women living in Brazil, Brazilian regions and States, from 1996 to 2013. For the trend analysis, the polynomial regression model was used, and a significant trend was considered when the estimated model obtained a p value <0.05. There was a tendency of increased mortality from breast cancer in Brazilian women (average increase of 0.18 per year; p <0.001), with regional differences, particularly in the age group 20–49 years (0.07 per year; p <0.001). The age group 50–69 years remained constant but had high average rates (37.14). More effective planning is needed to focus on the different scenarios of the Brazilian regions. Screening strategies for the incidence and mortality from breast cancer must also be rethought according to age group in the country.
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