The Perception-Behavior Dissociation in the Ultimatum Game in Unmedicated Patients With Major Depressive Disorders
The Perception-Behavior Dissociation in the Ultimatum Game in Unmedicated Patients With Major Depressive Disorders
复制标题
未接受药物治疗的重度抑郁症患者在最后通牒游戏中的知觉与行为分离
DOI：
10.1037/abn0000747
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发表时间：
2022-04-01
期刊：
影响因子：
--
通讯作者：
Zhou, Yuan
中科院分区：
文献类型：
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作者：
Jin, Yuening;Gao, Qinglin;Zhou, Yuan
重度抑郁症（MDD）患者表现出社会功能障碍，如MDD患者与对照组相比，在最后通牒游戏（UG）中接受不公平建议的比例较低。然而，其潜在机制在很大程度上仍然未知。在这项研究中，我们探讨了抑郁症患者是否改变了公平的看法或改变了感知行为的联系与对照组相比，使用多层次的调解框架。招募了68名未经药物治疗的MDD患者和55名对照组成员。采用广义线性混合效应模型和多水平结构方程模型，我们调查了公平水平之间的联系的差异，公平感知，并接受行为之间的两组玩UG。结果表明，抑郁症患者对不公平提议的接受率低于对照组。公平知觉调解公平水平和接受行为的两组参与者之间的关系时，他们与人类提案人，而不是计算机提案人。对照组的中介作用强于MDD患者。与对照组相比，MDD患者的公平感和接受行为之间的联系减弱。总之，抑郁症患者的能力受损，灵活地调整接受行为的基础上，在社会interactions.This研究表明，与对照组的成员相比，抑郁症患者更频繁地拒绝不公平的建议公平知觉。我们调查了潜在的机制，发现与对照组的成员相比，MDD患者并不认为相同的建议或多或少是公平的。然而，MDD患者在公平感知的基础上灵活调整接受行为的能力受损。
Patients with major depressive disorders (MDD) exhibit social dysfunction, as illustrated by the lower acceptance rate of unfair proposals in the Ultimatum Game (UG) among patients with MDD compared with a control group. However, the underlying mechanisms remain largely unknown. In this study, we explored whether patients with MDD had altered perceptions of fairness or altered perception-behavior linkages compared with the control group, using a multilevel moderated mediation framework. Sixty-eight unmedicated patients with MDD and 55 members of a control group were recruited. Using generalized linear mixed effects models and multilevel structural equation modeling, we investigated the differences in the linkages between fairness level, fairness perception, and acceptance behavior among the two groups playing the UG. The results showed that the patients with MDD had a lower acceptance rate of unfair proposals than the control group. Fairness perception mediated the relationship between fairness level and acceptance behavior for both groups of participants when they played with human proposers but not computer proposers. The mediation effect was stronger among the control group than among the MDD patients. The linkage between fairness perception and acceptance behavior was attenuated among the patients with MDD compared with the control group. In conclusion, MDD patients were impaired in their ability to flexibly adjust acceptance behavior based on fairness perception in social interactions.This study suggests that patients with major depressive disorders more frequently reject unfair proposals than members of a control group. We investigated the underlying mechanism and found that the patients with MDD did not perceive the same proposal as more or less fair compared with members of the control group. However, the patients with MDD were impaired in their ability to flexibly adjust acceptance behavior based on fairness perception.