Heroin-assisted treatment as a response to the public health problem of opiate dependence
Heroin-assisted treatment as a response to the public health problem of opiate dependence
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DOI：
10.1093/eurpub/12.3.228
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发表时间：
2002-09-01
影响因子：
4.4
通讯作者：
Van Ree, JM
中科院分区：
文献类型：
--
作者：
Fischer, B;Rehm, J;Van Ree, JM
注射吸毒（包括注射非法阿片剂）在许多国家造成严重的公共健康问题。研究表明，注射吸毒者感染艾滋病毒/艾滋病和B型和C型肝炎的风险更高，与毒品有关的死亡率也更高，犯罪活动也更频繁。美沙酮维持治疗是一些国家治疗非法阿片剂依赖的最主要药物疗法，其应用在国际上因治疗条例和提供方式而异。为了有效治疗那些之前对美沙酮维持治疗耐药的患者，一些国家一直在研究和/或考虑将海洛因辅助治疗作为阿片类药物治疗的补充形式。本文概述了国际上注射吸毒的流行率和阿片剂依赖问题，几个国家目前的阿片剂依赖治疗情况，以及澳大利亚、加拿大和某些欧洲国家正在进行或计划进行的海洛因辅助治疗试验的状况。
Injection drug use (involving the injection of illicit opiates) poses serious public health problems in many countries. Research has indicated that injection drug users are at higher risk for morbidity in the form of HIV/AIDS and Hepatitis B and C, and drug-related mortality, as well as increased criminal activity. Methadone maintenance treatment is the most prominent form of pharmacotherapy treatment for illicit opiate dependence in several countries, and its application varies internationally with respect to treatment regulations and delivery modes. In order to effectively treat those patients who have previously been resistant to methadone maintenance treatment, several countries have been studying and/or considering heroin-assisted treatment as a complementary form of opiate pharmacotherapy treatment. This paper provides an overview of the prevalence of injection drug use and the opiate dependence problem internationally, the current opiate dependence treatment landscape in several countries, and the status of ongoing or planned heroin-assisted treatment trials in Australia, Canada and certain European countries.