A tandem Heck-carbocyclization/Suzuki-coupling approach to the stereoselective syntheses of asymmetric 3,3-(diarylmethylene)indolinones
A tandem Heck-carbocyclization/Suzuki-coupling approach to the stereoselective syntheses of asymmetric 3,3-(diarylmethylene)indolinones
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DOI：
10.1021/jo050016d
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发表时间：
2005-04-29
影响因子：
3.6
通讯作者：
Player, MR
中科院分区：
文献类型：
--
作者：
Cheung, WS;Patch, RJ;Player, MR
本文报道了一种立体选择性合成（E）-3，3-（二芳基亚甲基）吲哚啉酮类化合物的高效、通用方法。详细介绍了影响产率和选择性的因素，即催化剂、配体和溶剂。
An efficient and versatile method for stereoselective synthesis of (E)-3,3-(diarylmethylene)indolinones by a palladium-catalyzed tandem Heck-carbocyclization/Suzuki-coupling sequence is presented. Factors influencing yield and selectivity, namely catalyst, coordinating ligand, and solvent, are detailed.