The landscape of knowledge translation interventions in cancer control: what do we know and where to next? A review of systematic reviews.
The landscape of knowledge translation interventions in cancer control: what do we know and where to next? A review of systematic reviews.
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DOI：
10.1186/1748-5908-6-130
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发表时间：
2011-12-20
期刊：
影响因子：
--
通讯作者：
KT for Cancer Control in Canada Project Research Team
中科院分区：
文献类型：
--
作者：
Brouwers MC;Garcia K;Makarski J;Daraz L;Evidence Expert Panel;KT for Cancer Control in Canada Project Research Team
需要有效的实施策略来优化癌症诊断，治疗，生存和临终关怀领域的进步。我们对系统评价进行了回顾，以更好地了解癌症控制实施策略的证据基础。使用三个数据库，我们进行了一次检索，并确定了2005年至2010年期间发表的针对消费者、专业人员、组织、监管或财务干预措施的英语系统性综述，这些综述仅在癌症背景下进行或部分进行了测试（主要关注点）;还考虑了通用或非癌症特异性综述。研究小组成员对数据进行了提取、评价和分析，并提出了推进该领域的研究思路。34篇系统性综述提供了19种独特干预措施的41份证据摘要，构成了证据基础。AMSTAR质量评级在2到10之间。团队成员将大多数干预措施评为有希望的，需要进一步研究，并确定了64个研究思路。虽然许多干预措施在癌症控制方面显示出有效性，但很少有评论能够明确得出支持或反对特定干预措施的结论。我们讨论了实施研究的复杂性，并提出建议，以推进这一领域的科学。
Effective implementation strategies are needed to optimize advancements in the fields of cancer diagnosis, treatment, survivorship, and end-of-life care. We conducted a review of systematic reviews to better understand the evidentiary base of implementation strategies in cancer control. Using three databases, we conducted a search and identified English-language systematic reviews published between 2005 and 2010 that targeted consumer, professional, organizational, regulatory, or financial interventions, tested exclusively or partially in a cancer context (primary focus); generic or non-cancer-specific reviews were also considered. Data were extracted, appraised, and analyzed by members of the research team, and research ideas to advance the field were proposed. Thirty-four systematic reviews providing 41 summaries of evidence on 19 unique interventions comprised the evidence base. AMSTAR quality ratings ranged between 2 and 10. Team members rated most of the interventions as promising and in need of further research, and 64 research ideas were identified. While many interventions show promise of effectiveness in the cancer-control context, few reviews were able to conclude definitively in favor of or against a specific intervention. We discuss the complexity of implementation research and offer suggestions to advance the science in this area.
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