Successful treatment for chromoblastomycosis caused by Fonsecaea monophora: a report of three cases in Guangdong, China
Successful treatment for chromoblastomycosis caused by Fonsecaea monophora: a report of three cases in Guangdong, China
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DOI：
10.1111/j.1439-0507.2008.01547.x
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发表时间：
2009-03-01
期刊：
影响因子：
4.9
通讯作者：
Sybren, De Hoog
中科院分区：
文献类型：
--
作者：
Zhang, Junmin;Xi, Liyan;Sybren, De Hoog
Fonsecaea pedrosoi 是着色芽生菌病最常见的病原体。 Fonsecaea monophora 是从 Fonsecaea pedrosoi 中分离出来的新种。在此，我们报告了三例由 F. monophora 引起的着色芽生菌病，并用特比萘芬和/或伊曲康唑成功治疗。描述了临床特征和真菌学参数。 3名患者中的2名在治疗早期接受了伊曲康唑和特比萘芬联合治疗，并在较短的疗程内完全治愈。
Fonsecaea pedrosoi is the most prevalent aetiological agent of chromoblastomycosis. Fonsecaea monophora is a new species segregated from Fonsecaea pedrosoi. Herein, we report on three cases of chromoblastomycosis caused by F. monophora that were successfully treated with terbinafine and/or itraconazole. Clinical characteristics and mycological parameters are described. Two of the three patients underwent combination therapy with itraconazole and terbinafine during early stages of treatment and were completely healed in a relatively short course of treatment.