Factors involved in the regulatory network of polyhydroxyalkanoate metabolism

Factors involved in the regulatory network of polyhydroxyalkanoate metabolism
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DOI:
10.1016/s0168-1656(00)00404-1
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发表时间:
2001-03-30
影响因子:
4.1
通讯作者:
Witholt, B
Witholt, B
中科院分区:
工程技术3区
文献类型:
--
作者:
Kessler, B;Witholt, B

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聚羟基烷酸酯(PHAs)是各种细菌在不平衡生长条件下积累起来的细菌储存材料。虽然PHA的产量较大,而且由于其塑料材料的特性而被研究,但人们对PHA积累的调节以及与一般细胞代谢的调节相互作用知之甚少。在这份报告中,我们指出了参与PHA代谢的调节机制的多样性,并提供了转录或酶水平上作用的因子的例子。(C)2001 Elsevier Science B.V.保留所有权利。
Polyhydroxyalkanoates (PHAs) are bacterial storage materials which are accumulated by various bacteria under unbalanced growth conditions. Although PHAs are produced in larger amounts and are studied because of their plastic material properties, not much is known about the regulation of PHA accumulation and the regulatory interactions with the general cell metabolism. In this report, we point out the diversity of regulatory mechanisms involved in PHA metabolism, and present examples for factors acting at the transcription or enzymatic level. (C) 2001 Elsevier Science B.V. All rights reserved.