A method to evaluate the feasibility of TMB chromatography for reduced efficiency and purity requirements based on discrete optimization

A method to evaluate the feasibility of TMB chromatography for reduced efficiency and purity requirements based on discrete optimization
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基于离散优化评估 TMB 色谱降低效率和纯度要求的可行性的方法

DOI:
10.1016/j.compchemeng.2007.01.001
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发表时间:
2007
期刊:
Comput. Chem. Eng.
影响因子:
--
通讯作者:
Weismantel R.
Weismantel R.
中科院分区:
--
文献类型:
--
作者:
Haus U.-U;Michaels D;Seidel-Morgenstern A;Weismantel R.

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本文介绍了一种基于组合优化的精确数学方法来分析连续线性逆流色谱过程。该分析基于一组给定的输入参数,特别包括纯度要求和每个区域的板数。作为分析的结果,要么得出给定参数集的不可行性证明,要么找到与输入要求相对应的可行解决方案。提供了有关数学组合子问题的详细信息。
This paper introduces an exact mathematical approach based on combinatorial optimization to analyze continuous linear countercurrent chromatographic processes. The analysis is based on a given set of input parameters including, in particular, purity requirements and number of plates per zone. As an outcome of the analysis either a proof of infeasibility is derived for a given set of parameters, or a feasible solution is found that is in correspondence with the input requirements. Details regarding the mathematical combinatorial subproblems are presented.
DOI: --
发表时间: 1992
期刊:
影响因子: --
作者:
C. Ching;K. Chu;K. Hidajat;M. S. Uddin
通讯作者: M. S. Uddin