MDS_IES_DB: a database of macronuclear and micronuclear genes in spirotrichous ciliates
MDS_IES_DB: a database of macronuclear and micronuclear genes in spirotrichous ciliates
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DOI：
10.1093/nar/gki130
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发表时间：
2005-01-01
影响因子：
14.9
通讯作者：
Landweber, LF
中科院分区：
文献类型：
--
作者：
Cavalcanti, ARO;Clarke, TH;Landweber, LF
纤毛原生动物有两种细胞核：大核（MAC）和微核（MIC）。在一些纤毛虫类中，例如螺旋毛虫，大多数基因在大核发育过程中经历多层 DNA 重排。由于这些过程，这些生物体为研究重组和基因重排机制提供了理想的系统。在这里，我们描述了一个包含所有螺菌基因的数据库，其中 MAC 和 MIC 版本均已测序，具有一致的注释并易于访问所有功能。查询数据库的界面可在 http://oxytricha.princeton.edu/dimorphism/database.htm 上找到。
Ciliated protozoa have two kinds of nuclei: Macronuclei (MAC) and Micronuclei (MIC). In some ciliate classes, such as spirotrichs, most genes undergo several layers of DNA rearrangement during macronuclear development. Because of such processes, these organisms provide ideal systems for studying mechanisms of recombination and gene rearrangement. Here, we describe a database that contains all spirotrich genes for which both MAC and MIC versions are sequenced, with consistent annotation and easy access to all the features. An interface to query the database is available at http://oxytricha.princeton.edu/dimorphism/database.htm.