Expression of PD-L1 correlates with pleomorphic morphology and histological patterns of non-small-cell lung carcinomas
Expression of PD-L1 correlates with pleomorphic morphology and histological patterns of non-small-cell lung carcinomas
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DOI：
10.1111/his.13466
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发表时间：
2018-05-01
期刊：
影响因子：
6.4
通讯作者：
Nicholson, Andrew G.
中科院分区：
文献类型：
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作者：
Kwong, Francois Ng Kee;Laggner, Ute;Nicholson, Andrew G.
AimsAs免疫调节治疗被整合到非小细胞肺癌的治疗方案中，我们的目的是前瞻性地收集在我们的机构评估的肿瘤的免疫组化概况的数据，并将其与肿瘤的形态学features.Methods and resultsImmunohistochemistry程序性死亡配体1（PD-L1）被认为是足够的，当>100肿瘤细胞被视为显微镜下。充分时，PD-L1染色评分为
AimsAs immunomodulatory therapy is being integrated into treatment regimens for non-small-cell lung carcinoma, we aimed to prospectively collect data on the immunohistochemical profile of tumours assessed in our institution and to correlate this with morphological tumour features.Methods and resultsImmunohistochemistry for programmed death-ligand 1 (PD-L1) was considered to be adequate when >100 tumour cells were seen microscopically. When adequate, PD-L1 staining was scored as