What Motivates Gay and Bisexual Men to Participate in PrEP-Related Research?

What Motivates Gay and Bisexual Men to Participate in PrEP-Related Research?
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DOI:
10.1080/19317611.2019.1634173
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发表时间:
2019-07-11
影响因子:
2
通讯作者:
Grov, Christian
Grov, Christian
中科院分区:
医学4区
文献类型:
--
作者:
D'Angelo, Alexa B.;Lopez-Rios, Javier;Grov, Christian

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暴露前预防(PrEP)已被证明在男同性恋者和双性恋者(GBM)等关键人群中预防艾滋病毒有效。然而,仍然需要让GBM参与PrEP行为和临床研究(例如,监测PrEP治疗级联中的依从性和保留率)。目的:我们报告了促使GBM参与PrEP行为研究的因素,目的是为未来的PrEP研究提供未来的招募工作信息。方法:在2015-2016年间,在纽约市使用PrEP的103名使用GBM的人完成了关于他们使用PrEP经验的定性访谈。参与者还被问及促使他们加入这项研究的因素。采用主题分析的方法对数据进行分析。结果:我们确定了5个显著的主题作为加入研究的理由:58.3%的人提到利他主义的原因,32%的人报告了对研究对象的求知欲,30.1%的人表示薪酬激励了他们,18.4%的人表示熟悉或转介到研究机构影响了他们的决定。结论:试图登记使用PrEP的GBM的研究人员可能受益于关注这一人群的利他主义和求知欲的本质。此外,研究人员可能受益于在不同的GBM社区之间建立熟悉度。这反过来可能有助于GBM成功地参与PrEP研究。
Preexposure prophylaxis (PrEP) has been demonstrated effective at preventing HIV among key populations like gay and bisexual men (GBM). Yet, there remains a continued need to engage GBM in PrEP behavioral and clinical research (e.g., to monitor adherence and retention in the PrEP treatment cascade). Objectives: We report on the factors motivating GBM to participate in a PrEP behavioral study, with the aim of our results to inform future recruitment efforts for future PrEP research. Methods: In 2015-2016, 103 PrEP-using GBM in New York City completed qualitative interviews about their experiences on PrEP. Participants were also asked about factors that motivated them to join the study. Thematic analysis was used analyze the data. Results: We identified 5 salient themes as rationale for joining the study: 58.3% cited altruistic reasons, 32% reported intellectual curiosity in the subject matter, 30.1% indicated that remuneration inspired them, 18.4% indicated that familiarity or referral to the research institute influenced their decision. Conclusions: Researchers attempting to enroll PrEP-using GBM may benefit from attending to the altruistic and intellectually curious nature of this population. Further, researchers may benefit from establishing familiarity among diverse communities of GBM. This in turn may contribute to the successful engagement of GBM for PrEP research.