Responses of neurons in the inferior colliculus to dynamic interaural phase cues: evidence for a mechanism of binaural adaptation.
Responses of neurons in the inferior colliculus to dynamic interaural phase cues: evidence for a mechanism of binaural adaptation.
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下丘神经元对动态耳间相位线索的反应：双耳适应机制的证据。
DOI：
10.1152/jn.2000.83.3.1356
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发表时间：
2000
影响因子：
2.5
通讯作者：
A. Palmer
中科院分区：
文献类型：
--
作者：
D. McAlpine;D. Jiang;T. M. Shackleton;A. Palmer
在乌拉坦麻醉的豚鼠下丘(IC)获得对人类感觉为运动的声音刺激的反应。三角形和正弦耳间相位调制(IPM)产生动态变化的耳间相位差(IPDS)，用于呈现不同深度、方向、中心和表观运动速率的刺激。许多神经元似乎对动态IPD很敏感，任何给定IPD的反应都强烈依赖于刺激刚刚通过的IPD。然而，是反应的时间模式，而不是IPM中的运动线索，决定了对运动深度、方向和中心轨迹等特征的敏感性。IPM仅限于IPD反应区的中心，诱发的放电频率低于刺激从外部穿过IPD反应区或上下侧翼时的放电率。当刺激先向一个方向穿过反应区，再向另一个方向移动时，相同的IPD诱发不同的反应时，对远离IPD反应区中心的反应总是低于向中心移动的反应。当IPD越靠近运动方向反转的中心时，对后续运动的反应就越低。在任何情况下，我们都没有发现任何证据表明神经元在所有条件下都倾向于一个运动方向而不是另一个方向。我们的结论是，IC神经元对IPM刺激的反应本身并不取决于刺激的历史，而是取决于它们对刺激的反应的历史，而与引起这些反应的特定运动线索无关。这些数据与驻留在双耳整合或以上的适应机制的参与是一致的。我们的结论是，我们的数据没有提供哺乳动物听觉中脑中涉及动态IPD线索的专门运动检测的证据。
Responses to sound stimuli that humans perceive as moving were obtained for 89 neurons in the inferior colliculus (IC) of urethan-anesthetized guinea pigs. Triangular and sinusoidal interaural phase modulation (IPM), which produced dynamically varying interaural phase disparities (IPDs), was used to present stimuli with different depths, directions, centers, and rates of apparent motion. Many neurons appeared sensitive to dynamic IPDs, with responses at any given IPD depending strongly on the IPDs the stimulus had just passed through. However, it was the temporal pattern of the response, rather than the motion cues in the IPM, that determined sensitivity to features such as motion depth, direction, and center locus. IPM restricted only to the center of the IPD responsive area, evoked lower discharge rates than when the stimulus either moved through the IPD responsive area from outside, or up and down its flanks. When the stimulus was moved through the response area first in one direction and then back in the other, and the same IPDs evoked different responses, the response to the motion away from the center of the IPD responsive area was always lower than the response to the motion toward the center. When the IPD was closer at which the direction of motion reversed was to the center, the response to the following motion was lower. In no case did we find any evidence for neurons that under all conditions preferred one direction of motion to the other. We conclude that responses of IC neurons to IPM stimuli depend not on the history of stimulation, per se, but on the history of their response to stimulation, irrespective of the specific motion cues that evoke those responses. These data are consistent with the involvement of an adaptation mechanism that resides at or above the level of binaural integration. We conclude that our data provide no evidence for specialized motion detection involving dynamic IPD cues in the auditory midbrain of the mammal.
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影响因子：
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作者：
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DOI：
10.1152/jn.1998.80.6.3062
发表时间：
1998
期刊：
Journal of neurophysiology.
影响因子：
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作者：
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通讯作者：
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影响因子：
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