HIV vaccine trial preparedness among Spanish-speaking Latinos in the US
HIV vaccine trial preparedness among Spanish-speaking Latinos in the US
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DOI：
10.1080/09540120600872711
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发表时间：
2007-01-01
影响因子：
1.7
通讯作者：
Ortiz, D. J.
中科院分区：
文献类型：
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作者：
Brooks, R. A.;Newman, P. A.;Ortiz, D. J.
在美国，拉美裔在艾滋病毒/艾滋病医学研究中的代表性不足。尽管拉美裔人受到艾滋病毒/艾滋病的影响不成比例，但他们可能不愿参与艾滋病毒疫苗试验。对从加利福尼亚州洛杉矶的两个社区医疗保健组织招募的32名讲西班牙语的拉丁裔进行了三个焦点小组。制定了一份定性焦点小组访谈指南，以探讨与参与艾滋病毒疫苗试验有关的关切、激励因素和意图。对政府的不信任和恐惧成为与不愿参与艾滋病毒疫苗试验有关的重要主题。参与试验的具体问题包括：(1)对疫苗引起的艾滋病毒感染的恐惧，(2)身体副作用，(3)耻辱和(4)虚假诱导的艾滋病毒阳性检测结果及其社会影响。参与HIV疫苗试验的动机包括：(1)激励，(2)参与研究的便利性，(3)充分和适当的研究信息，(4)个人利益和(5)利他主义。促进拉美裔参与艾滋病毒疫苗试验的干预措施应解决对政府资助的艾滋病毒/艾滋病医学研究的不信任和恐惧，增加获得临床试验的机会和便利，消除对疫苗引起感染的恐惧，消除艾滋病毒/艾滋病污名，并提高对艾滋病毒/艾滋病与拉丁裔社区相关性的认识。
Latinos are under-represented in HIV/AIDS medical research in the US. Although they are disproportionately impacted by HIV/AIDS, Latinos may be reluctant to participate in HIV vaccine trials. Three focus groups were conducted with 32 Spanish-speaking Latinos recruited from two community-based healthcare organizations in Los Angeles, California. A qualitative focus group interview guide was developed to explore concerns, motivators and intentions in regard to participation in HIV vaccine trials. Mistrust and fear of government emerged as important themes related to reluctance to participate in an HIV vaccine trial. Specific concerns regarding trial participation included: (1) fear of vaccine-induced HIV infection, (2) physical side effects, (3) stigma and (4) false-induced HIV-positive test results and their social repercussions. Motivators for enrolling in an HIV vaccine trial included: (1) incentives, (2) convenience of participating in a study, (3) sufficient and appropriate study information, (4) personal benefits and (5) altruism. Interventions to facilitate participation by Latinos in HIV vaccine trials, should address mistrust and fear of government-sponsored HIV/AIDS medical research, increase access to and convenience of clinical trials, address fear of vaccine-induced infection, combat HIV/AIDS stigma and raise awareness of the relevance of HIV/AIDS to Latino communities.