Recent trends in seroprevalence of rubella in Korean women of childbearing age: a cross-sectional study
Recent trends in seroprevalence of rubella in Korean women of childbearing age: a cross-sectional study
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DOI：
10.1136/bmjopen-2019-030873
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发表时间：
2020-01-01
期刊：
影响因子：
2.9
通讯作者：
Lee, Eun Hee
中科院分区：
文献类型：
--
作者：
Choi, Rihwa;Oh, Yejin;Lee, Eun Hee
本研究的目的是了解韩国育龄妇女(15-49岁)风疹特异性抗体(抗风疹抗体)的血清学状况。设计回顾横断面研究。在韩国开展以人群为基础的横断面研究。受试者2010年1月至2017年12月，从实验室信息系统获得了15-49岁的韩国妇女的风疹特异性抗体检测结果。结果2010年至2017年，对328426名15~49岁朝鲜族妇女到全国1438家私立产科诊所就诊的抗风疹抗体检测结果按检测年份、年龄、队列和地区进行了回顾性分析。在为期8年的研究期间，未接种疫苗的妇女比例从7.8%到9.7%不等。多变量调整的Logistic回归模型显示，与2010年相比，2017年对风疹免疫的几率(抗风疹抗体检测阳性和可疑)在40多岁的妇女中、在追赶前的队列中以及在仁川、釜山、庆尚南道、南北全罗州和济州省的妇女中降低(P
ObjectivesThe aim of this study was to investigate the immunity against rubella using the serological status of rubella-specific IgG antibodies (antirubella IgG) in Korean women of childbearing age (15-49 years).DesignRetrospective cross-sectional study.SettingPopulation-based cross-sectional study in South Korea.ParticipantsBetween January 2010 and December 2017, test results from Korean women aged 15-49 years who had visited an obstetric private clinic (nationwide institutions) and had requested rubella-specific IgG antibody tests from Green Cross Laboratories were obtained from the laboratory information system.ResultsBetween 2010 and 2017, antirubella IgG test results from 328 426 Korean women aged 15-49 years who had visited private obstetric clinics (1438 institutions nationwide) were retrospectively analysed by tested year, age, cohort and geographic regions. Over the 8-year study period, the rate of unimmunised women ranged from 7.8% to 9.7%. Multivariable-adjusted logistic regression models showed that the odds of being immune to rubella (positive and equivocal results of antirubella IgG test) were lower in 2017 compared with 2010, in women in their 40s, in a pre-catch-up cohort and in women living in Incheon, Busan, South Gyeongsang, North and South Jeolla and Jeju provinces (p
影响因子：
3.7
作者：
Yamada T;Mochizuki J;Hanaoka M;Hashimoto E;Ohkuchi A;Ito M;Kubo T;Nakai A;Saito S;Unno N;Matsubara S;Minakami H
通讯作者：
Minakami H