Transformation of Blood Group Substance by Bacterial Enzyme
Transformation of Blood Group Substance by Bacterial Enzyme
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细菌酶对血型物质的转化
DOI：
10.2183/pjab1945.29.460
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发表时间：
1953
期刊：
影响因子：
--
通讯作者：
S. Masaki
中科院分区：
文献类型：
--
作者：
S. Iseki;S. Masaki
此前，Iseki和Okada 1‘发现Terdium产生一种专门分解A类物质的酶，然后Iseki和Tsunoda Z’发现Fulminans产生一种专门分解0类物质的酶。对这一问题的进一步研究使我们发现，氚梭菌的酶与A组物质反应，使其特异性消失，而代之以产生0物质。本文报道了这一结果。现在，这里所说的0物质是艾斯勒-卡加亚的异嗜性抗原。然而，根据摩根和沃特金斯的说法，人类唾液中的0物质与人类血细胞中的0物质是不同的，前者被称为H物质。
Previously, Iseki and Okada 1' discovered that Clostridium tertium produces an enzyme which specifically decomposes group A substance, and then Iseki and Tsunoda Z' found that Bacillus f ulminans produces an enzyme which specifically decomposes 0 substance. Further study on the subject led us to the discovery that the enzyme of Clostridium tertium, reacting with group A substance, makes its specificity disappear and instead produces 0 substance. The result is reported in this paper. Now, what is called 0 substance here is an Eisler-Kagaya's heterophile antigen. According to Morgan and Watkins however, 0 substance in human saliva is distinguished from that in human blood cells, the former being called H substance.