EFFECT OF SITE-SPECIFIC MODIFICATION ON RESTRICTION ENDONUCLEASES AND DNA MODIFICATION METHYLTRANSFERASES
EFFECT OF SITE-SPECIFIC MODIFICATION ON RESTRICTION ENDONUCLEASES AND DNA MODIFICATION METHYLTRANSFERASES
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DOI：
10.1093/nar/22.17.3640
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发表时间：
1994-09-01
影响因子：
14.9
通讯作者：
RASCHKE, E
中科院分区：
文献类型：
--
作者：
MCCLELLAND, M;NELSON, M;RASCHKE, E
限制性内切核酸酶与DNA具有位点特异性相互作用，其通常可被位点特异性DNA甲基化和其他位点特异性DNA修饰抑制。然而，这种抑制通常不能预测。对超过320种限制性核酸内切酶的经验获得的这些影响的数据制成表格。此外，沿着了已知位点特异性DNA修饰甲基转移酶及其特异性的表格，以及克隆基因的EMBL数据库登录号。
Restriction endonucleases have site-specific interactions with DNA that can often be inhibited by site-specific DNA methylation and other site-specific DNA modifications. However, such inhibition cannot generally be predicted. The empirically acquired data on these effects are tabulated for over 320 restriction endonucleases. In addition, a table of known site-specific DNA modification methyltransferases and their specificities is presented along with EMBL database accession numbers for cloned genes.