Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome based on NMR techniques
Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome based on NMR techniques
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DOI：
10.1007/s11434-007-0389-4
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发表时间：
2007-11-01
影响因子：
--
通讯作者：
Han Ding
中科院分区：
文献类型：
--
作者：
Li Lin;Wang JianNong;Han Ding
采用核磁共振技术对气虚血瘀证大鼠尿液进行代谢组学分析，并与正常大鼠尿液进行比较。气虚血瘀证大鼠尿中甲酸、肌酐、2-酮戊二酸（2-OG）、柠檬酸、牛磺酸、氧化三甲胺（TMAO）、琥珀酸和马尿酸的相对含量发生变化。这些结果为认识气虚血瘀证的发病机制和治疗提供了依据。
Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome has been performed by comparison with those of normal rats based on NMR techniques. The relative contents of formate, creatinine, 2-oxoglutarate (2-OG), citrate, taurine, trimethylamine-N-oxide(TMAO), succinate and hippurate in the urine of the rats with Qi deficiency and blood stasis syndrome have been changed. These results have provided evidence for understanding the mechanism and the therapy of Qi deficiency and blood stasis syndrome.