Three dimensional myoarchitecture of the human tongue determined in vivo by diffusion tensor imaging with tractography
Three dimensional myoarchitecture of the human tongue determined in vivo by diffusion tensor imaging with tractography
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DOI：
10.1002/jmri.21022
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发表时间：
2007-09-01
影响因子：
4.4
通讯作者：
Gilbert, Richard J.
中科院分区：
文献类型：
--
作者：
Gaige, Terry A.;Benner, Thomas;Gilbert, Richard J.
目的：利用纤维束成像技术，利用扩散张量成像 (DTI) 来研究涉及人舌内在和外在肌纤维群的解剖关系。材料和方法：使用 1.5T 两次重聚焦自旋回波 DTI 脉冲序列、各向同性 3 x 3 x 3 mm(3) 体素、b 值 500 秒/mm(2) 和 90 个不同扩散获得人舌体内图像敏化梯度方向。沿着每个体素中的最大扩散向量生成多体素束。使用定制纤维跟踪软件和图像与已知解剖结构进行比较来可视化数据。结果：DTI 纤维束成像描绘了人类舌头的完整三维 (3D) 肌结构，特别展示了内在和外在肌纤维群之间的几何关系。这些结果定义了关键的外在纤维群与纵向、横向和垂直排列的内在纤维融合的方式。结论：当前的结果首次展示了在体内使用 DTI 纤维束成像来可视化人类舌头的完整结构解剖结构，并使我们能够考虑基本的结构功能关系。
Purpose: To study the anatomical relationships involving the intrinsic and extrinsic myofiber populations of the human tongue employing diffusion tensor imaging (DTI) with tractography.Materials and Methods: Images of the human tongue In vivo were obtained using a twice-refocused spin echo DTI pulse sequence at 1.5T, isotropic 3 x 3 x 3 mm(3) voxels, b-value 500 seconds/mm(2), and 90 different diffusion sensitizing gradient directions. Multivoxel tracts were generated along the vectors of maximal diffusion in each voxel. The data was visualized using custom fiber tracking software and images compared with known anatomy.Results: DTI tractography depicts the complete three-dimensional (3D) myoarchitecture of the human tongue, specifically demonstrating the geometric relationships between the intrinsic and extrinsic myofiber populations. These results define the manner in which key extrinsic fiber populations merge with the longitudinally-, transversely-, and vertically-aligned intrinsic fibers.Conclusion: The current results display for the first time the use of DTI tractography in vivo to visualize the complete structural anatomy of the human tongue and allow us to consider fundamental structure-function relationships.