Age-related decline of sleep-dependent consolidation
Age-related decline of sleep-dependent consolidation
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DOI：
10.1101/lm.569407
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发表时间：
2007-07-01
影响因子：
2
通讯作者：
Ivry, Richard B.
中科院分区：
文献类型：
--
作者：
Spencer, Rebecca M. C.;Gouw, Arvin M.;Ivry, Richard B.
在运动技能学习之后观察到睡眠依赖性记忆巩固：相对于没有睡眠的同等间隔，在包含睡眠的12小时时段内，表现改善更大。在这里，我们研究了老年人是否在序列学习任务中表现出睡眠依赖性巩固。参与者接受了两个序列学习任务之一的培训。在包括睡眠的12小时休息后和不包括睡眠的12小时休息后评估性能。老年人和年轻人的初始学习程度相似。然而，老年人的表现在睡眠后并没有改善，这提供了睡眠依赖性巩固随着年龄的增长而减少的证据。
Sleep- dependent memory consolidation is observed following motor skill learning: Performance improvements are greater over a 12- h period containing sleep relative to an equivalent interval without sleep. Here we examined whether older adults exhibit sleep- dependent consolidation on a sequence learning task. Participants were trained on one of two sequence learning tasks. Performance was assessed after a 12- h break that included sleep and after a 12- h break that did not include sleep. Older and younger adults showed similar degrees of initial learning. However, performance of the older adults did not improve following sleep, providing evidence that sleep- dependent consolidation is diminished with age.