RELATIVE CONTRIBUTION OF VERTEBRAL BODY AND POSTERIOR ARCH IN FEMALE AND MALE LUMBAR SPINE PEAK BONE MASS
RELATIVE CONTRIBUTION OF VERTEBRAL BODY AND POSTERIOR ARCH IN FEMALE AND MALE LUMBAR SPINE PEAK BONE MASS
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DOI：
10.1007/bf01623350
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发表时间：
1994-09-01
影响因子：
4
通讯作者：
BONJOUR, JP
中科院分区：
文献类型：
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作者：
FOURNIER, PE;RIZZOLI, R;BONJOUR, JP
峰值骨量（PBM）是诊断骨质疏松症的重要参考值。它通常是通过测定年轻健康成人骨骼给定部位的面积骨矿物质密度（BMD，单位为g/cm（2））来确定的。该测量同时考虑了扫描骨的厚度和综合矿物质密度。因此，它应该是抵抗机械应力的主要决定因素。然而，在腰椎中，尽管男性的腰椎椎体体积较大，但通过双能同位素或X线（DXA）吸收测定法在前后位视图中确定的平均BMD在男性和女性年轻健康成人之间没有差异。女性后椎弓对骨密度的贡献比男性大，这可以解释这种明显的差异。为了阐明这一问题，我们在65名（32名男性和33名女性）年龄在20-35岁的年轻健康成年人中测定了椎体（VB）和后椎弓（VA）对L2-3的BMD和骨矿物质含量（BMC）的相对贡献，这些BMD和BMC是使用DXA前后扫描和侧位（lat）扫描测量的。在年轻健康成人中，前后位视图中的平均BMC与侧位扫描（包括VB和VA）确定的总BMC无显著差异。这使得我们可以通过从BMC-ap中减去VB BMC-lat来计算VA BMC。结果表明，男性的BMC-ap平均值显著大于女性（男性/女性比率（平均值+/- SEM）：1.16 +/- 0.05，p
Peak bone mass (PBM) is an important reference value in the diagnosis of osteoporosis. It is usually established by determining the areal bone mineral density (BMD in g/cm(2)) for a given site of the skeleton in young healthy adults. This measurement takes into account both the thickness and the integrated mineral density of the bone scanned. It should therefore be a major determinant of the resistance to mechanical stress. However, in lumbar spine the mean BMD as determined by dual-energy either isotopic or X-ray (DXA) absorptiometry in antero-posterior tap) view was repeatedly found not to be different between male and female young healthy adults despite the greater volume of lumbar vertebral bodies in males. A greater contribution of the posterior vertebral arch to areal BMD-ap in females than in males could account for such an apparent discrepancy. In order to clarify this issue we have determined in 65 (32 male and 33 female) young healthy adults aged 20-35 years the relative contribution of the vertebral body (VB) and posterior vertebral arch (VA) to BMD and bone mineral content (BMC) of L2-3 measured by both antero-posterior and lateral (lat) scanning using DXA. In young healthy adults mean BMC in antero-posterior view was found not to be significantly different from the total BMC determined by lateral scanning including both VB and VA. This allowed us then to calculate the VA BMC by substracting VB BMC-lat from BMC-ap. The results indicated that the mean value for males was significantly greater than that for females for BMC-ap (male/female ratio (mean +/- SEM): 1.16 +/- 0.05, p