Microelectrode Recording for Deep Brain Stimulation of the Subthalamic Nucleus in Patients with Advanced Parkinson's Disease: Advantage or Loss of Time?
Microelectrode Recording for Deep Brain Stimulation of the Subthalamic Nucleus in Patients with Advanced Parkinson's Disease: Advantage or Loss of Time?
复制标题
DOI：
10.5137/1019-5149.jtn.23307-18.3
复制
发表时间：
2019-01-01
影响因子：
0.8
通讯作者：
Temel, Yasin
中科院分区：
文献类型：
--
作者：
Kocabicak, Ersoy;Alptekin, Onur;Temel, Yasin
目的：探讨微电极记录（MER）对帕金森病（PD）患者丘脑底核深部脑刺激（DBS）手术所需时间的影响。 材料和方法：计算 24 例 PD 患者的第一侧和第二侧将 MER 纳入 DBS 手术所需的时间。对第一侧和第二侧每个轨迹上使用的微电极数量以及第一侧和第二侧每个轨迹上植入的永久电极的百分比进行了量化。 结果：使用 MER 的第一侧、第二侧和整个手术的平均时间分别为 23.4 +/- 6.2 分钟、17.4 +/- 6.5 分钟和 41.2 +/- 6.3 分钟。 75% 的患者将永久电极植入第一侧的计划目标部位，61% 的患者将永久电极植入第二侧。结论：MER 延长了进行 DBS 手术所需的时间。然而，在手术过程中，它可以提供有关电极神经生理学位置的实时信息，并在计划目标未产生令人满意的结果时帮助手术团队选择替代目标。
AIM: To investigate the effect of using microelectrode recording (MER) on the length of time required to carry out a deep brain stimulation (DBS) procedure of the subthalamic nucleus in patients with Parkinson's disease (PD).MATERIAL and METHODS: The time required to include MER in the DBS operation was calculated for the first and second sides in 24 patients with PD. The number of microelectrodes used on each trajectory for the first and second sides, and the percentage of permanent electrodes implanted on each trajectory for the first and second sides, were quantified.RESULTS: The average times taken to use MER were 23.4 +/- 6.2 minutes, 17.4 +/- 6.5 minutes, and 41.2 +/- 6.3 minutes for the first side, second side and total procedure, respectively. In 75% of patients, the permanent electrode was implanted at the planned target site for the first side, and in 61% of patients for the second side.CONCLUSION: MER extends the time required to carry out the DBS procedure. However, during surgery, it provides real-time information on the electrodes' neurophysiological locations and helps the surgical team choose an alternative target if the planned target does not produce satisfying results.