High-resolution CT findings of severe acute respiratory syndrome at presentation and after admission
High-resolution CT findings of severe acute respiratory syndrome at presentation and after admission
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DOI：
10.2214/ajr.182.1.1820039
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发表时间：
2004-01-01
影响因子：
5
通讯作者：
Nicolaou, S
中科院分区：
文献类型：
--
作者：
Müller, NL;Ooi, GC;Nicolaou, S
OBJECTIVE.本研究的目的是评估严重急性呼吸综合征（SARS）患者入院时和入院后的高分辨率CT（HRCT）表现。本文回顾了29例SARS患者的HRCT表现，并与X线表现进行了比较。HRCT扫描采用1mm（n = 28）或2mm（n = 1）准直。X线片和HRCT扫描由两名观察员独立审查，并达成一致意见。所有患者在就诊时HRCT均异常。这12例患者中有8例在X线片上表现正常。主要HRCT表现为单侧（n = 6）或双侧（n = 2）磨玻璃影或局灶性单侧（n = 2）或双侧（n = 2）实变区。所有患者在随访时均显示疾病进展。随访CT扫描的主要HRCT结果包括单侧（n = 2）或双侧毛玻璃影（n = 13），单侧（n = 2）或双侧实变（n = 5），或混合双侧毛玻璃影衰减、实变和网状影（n = 3）。8例患者出现网状结构伴结构性变形和轻度牵拉性支气管扩张。HRCT可以显示SARS患者的实质异常，而这些患者在就诊时的X线片上表现正常。在住院患者中获得的随访CT扫描显示在一小部分患者中与纤维化一致的结果。
OBJECTIVE. The aim of this study was to assess the high-resolution CT (HRCT) findings at presentation and after hospital admission in patients with severe acute respiratory syndrome (SARS).MATERIALS AND METHODS. We reviewed the HRCT findings at presentation (n 12) and after hospital admission (n = 25) of 29 patients with SARS and compared the HRCT findings with the radiographic findings. HRCT scans were obtained using 1-mm (n = 28) or 2-mm (n = 1) collimation. The radiographs and HRCT scans were reviewed independently by two observers who reached a decision by consensus.RESULTS. All patients had abnormal findings on HRCT at presentation. Eight of these 12 patients had normal findings on radiographs. The predominant HRCT findings at presentation consisted of unilateral (n = 6) or bilateral (n = 2) ground-glass opacities or focal unilateral (n = 2) or bilateral (n = 2) areas of consolidation. All patients showed progression of disease on follow-up. The predominant HRCT findings on follow-up CT scans consisted of unilateral (n = 2) or bilateral ground-glass opacities (n = 13), unilateral (n = 2) or bilateral consolidation (n = 5), or a mixed bilateral pattern of ground-glass attenuation, consolidation, and reticulation (n = 3). Reticulation with associated architectural distortion and mild traction bronchiectasis was present in eight patients.CONCLUSION. HRCT can show parenchymal abnormalities in patients with SARS who have normal findings on radiographs at presentation. Follow-up CT scans obtained in hospitalized patients show findings consistent with fibrosis in a small percentage of patients.